HHLA3 and NMI

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1103

Data Source:
BioGRID (two hybrid, two hybrid, affinity chromatography technology, two hybrid)
HPRD (two hybrid)

		HHLA3	NMI
Description		HERV-H LTR-associating 3	N-myc and STAT interactor
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Extracellular Space Nucleus Nucleoplasm Cytoplasm Cytosol Membrane
	Molecular Function	Protein Binding	Transcription Coregulator Activity Protein Binding Identical Protein Binding
	Biological Process		Macrophage Activation Involved In Immune Response Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of Cell Population Proliferation Response To Virus Negative Regulation Of Interferon-alpha Production Negative Regulation Of Interferon-beta Production Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Innate Immune Response Negative Regulation Of Innate Immune Response Positive Regulation Of Inflammatory Response Interferon-gamma-mediated Signaling Pathway Negative Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Protein K48-linked Ubiquitination
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Proportion of activated microglia (inferior temporal cortex) ( 30679421)	Blood protein levels ( 28240269)
Interacting Genes		3 interacting genes: FLNA MDFI NMI	60 interacting genes: BRAT1 BRCA1 BRMS1 C1orf216 C9orf72 CDKN2A CDKN2D CNKSR3 CNOT7 COPS7B CYP2E1 EMILIN1 EPC2 EXOSC5 GART GCSH GOLGA8EP HDDC3 HGS HHLA3 HOXC9 HSPA8 HSPH1 IFI35 KDM1A LCA5L LSM4 MAD2L1BP MCPH1 MORF4L1 MTMR6 MTMR9 MYC MYCN MYOM3 NECAP2 POMZP3 PSMA1 RYBP SCEL SFR1 SH3GLB2 SINHCAF SNAPC5 SOX10 STAT1 STAT3 STAT4 STAT5A STAT5B STAT6 THAP8 TRAF5 TRIM72 TRIP12 TUBA3C TUBA3E TXLNA TXLNB UBE2I
Entrez ID		11147	9111
HPRD ID		05083	04632
Ensembl ID		ENSG00000197568	ENSG00000123609
Uniprot IDs		Q9XRX5	Q13287
PDB IDs
Enriched GO Terms of Interacting Partners?
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