SLC38A3 and HMGN1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		SLC38A3	HMGN1
Description		solute carrier family 38 member 3	high mobility group nucleosome binding domain 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Apical Plasma Membrane	Chromatin Nucleus Nucleoplasm Cytoplasm
	Molecular Function	L-histidine Transmembrane Transporter Activity Amino Acid Transmembrane Transporter Activity L-alanine Transmembrane Transporter Activity L-asparagine Transmembrane Transporter Activity L-glutamine Transmembrane Transporter Activity Symporter Activity Antiporter Activity	DNA Binding Chromatin Binding Protein Binding Nucleosomal DNA Binding
	Biological Process	Amino Acid Transmembrane Transport Sodium Ion Transport Amino Acid Transport Asparagine Transport Glutamine Transport Brain Development Female Pregnancy L-alanine Transport Histidine Transport Cellular Response To Potassium Ion Starvation Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Acidic PH L-histidine Transmembrane Transport Transport Across Blood-brain Barrier Positive Regulation Of Glutamine Transport	Pyrimidine Dimer Repair By Nucleotide-excision Repair Transcription-coupled Nucleotide-excision Repair Chromatin Organization Regulation Of Transcription By RNA Polymerase II Response To UV-B Response To UV-C Positive Regulation Of DNA-templated Transcription, Elongation Regulation Of Development, Heterochronic Post-embryonic Camera-type Eye Morphogenesis Regulation Of Epithelial Cell Proliferation Positive Regulation Of NAD+ ADP-ribosyltransferase Activity
Pathways		Amino acid transport across the plasma membrane	Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER
Drugs		Histidine Asparagine
Diseases
GWAS		Body mass index ( 26426971) Conotruncal heart defects (maternal effects) ( 28468790) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 34021172) Immature fraction of reticulocytes ( 32888494) Reticulocyte fraction of red cells ( 32888494) Sleep duration (short sleep) ( 30846698) Smoking status (ever vs never smokers) ( 30643258)	Apolipoprotein A1 levels ( 33730874) LDL cholesterol levels ( 32203549) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		4 interacting genes: COL6A2 HMGN1 SETDB1 TNFSF14	26 interacting genes: CAMSAP3 CDC42 CHEK2 EP300 ETS2 GSK3A HMGN2 HPF1 IRF2 KLF13 LIG4 MDM2 NFE2 PARP1 PPP1CC PRKACA PRKACG PRKCA RPS6KA3 RPS6KA4 RPS6KA5 SLC38A3 SPP1 TERF2 TMEM121B YWHAZ
Entrez ID		10991	3150
HPRD ID		11980	01231
Ensembl ID		ENSG00000188338	ENSG00000205581
Uniprot IDs		Q99624	P05114 Q6NSG7
PDB IDs
Enriched GO Terms of Interacting Partners?
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