COPS6 and TRDMT1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		COPS6	TRDMT1
Description		COP9 signalosome subunit 6	tRNA aspartic acid methyltransferase 1
Image
GO Annotations	Cellular Component	Nucleoplasm Cytosol COP9 Signalosome Perinuclear Region Of Cytoplasm	Nucleoplasm Cytoplasm
	Molecular Function	Protein Binding Metallopeptidase Activity Isopeptidase Activity	RNA Binding TRNA Methyltransferase Activity TRNA (cytosine-5-)-methyltransferase Activity
	Biological Process	Protein Deneddylation	Response To Amphetamine TRNA Modification TRNA Methylation TRNA Stabilization
Pathways		DNA Damage Recognition in GG-NER Formation of TC-NER Pre-Incision Complex Cargo recognition for clathrin-mediated endocytosis Neddylation	tRNA modification in the nucleus and cytosol
Drugs			Pentamidine S-adenosyl-L-homocysteine Glycerin
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Aspartate aminotransferase levels ( 33547301) Platelet count ( 32888494) Platelet distribution width ( 32888494) Plateletcrit ( 32888494) Telomere length ( 24478790)
Interacting Genes		94 interacting genes: ANXA1 ANXA7 ASH2L BFSP2 BTBD2 C1orf174 C4orf17 CASP3 CASP6 CASP7 CASP8 CCBE1 CCDC106 CDH10 CDKN1A CDKN2C CHRNB1 COPS2 COPS3 COPS4 COPS5 COPS7B COPS8 COPS9 COX17 COX5A CRELD1 CUL1 CUL5 DIS3L2 DLEU1 EDN1 EIF3E EMD EP300 ERH FAU GPS1 HMOX2 LAMA4 LPL MAP3K1 MAP7D1 MAPK1 MAPK6 MAPKAPK3 MIF MNAT1 MYCBP NEDD8 NR3C1 ORAI2 PAEP PAFAH1B3 PBX2 PDZK1IP1 PFKL PHYHIP PMF1 PRKRA PSAP PSMD11 PTEN QTRT1 RAB27A RBX1 RFC5 ROGDI RPA2 RPL15 S100A10 SAT1 SERPINA5 SERPINB9 SHANK3 SHC3 SLC2A1 SMN1 SNRPG STK40 STX5 SULT1E1 TDGF1 TK1 TP53 TP63 TRDMT1 TRIB3 USHBP1 VIM WIPI2 ZEB2 ZFHX3 ZNF24	14 interacting genes: APP COPS6 DDX24 EEF1A1 GBE1 LRIF1 NFRKB RBM48 SETDB1 SNRPD3 STX1A TBC1D2B UNC119 UTP14A
Entrez ID		10980	1787
HPRD ID		16735	16001
Ensembl ID		ENSG00000168090	ENSG00000107614
Uniprot IDs		Q7L5N1	A0A0U1U562 B4DQZ2 O14717 Q6ICS7 Q7Z3E4
PDB IDs		4D10 4D18 4QFT 4R14 4WSN 6R6H 6R7F 6R7H 6R7I	1G55
Enriched GO Terms of Interacting Partners?
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