KDELR1 and CCR9

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		KDELR1	CCR9
Description		KDEL endoplasmic reticulum protein retention receptor 1	C-C motif chemokine receptor 9
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Cis-Golgi Network Integral Component Of Membrane Transport Vesicle COPI-coated Vesicle Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Plasma Membrane Integral Component Of Plasma Membrane External Side Of Plasma Membrane Cell Surface
	Molecular Function	KDEL Sequence Binding Protein Binding ER Retention Sequence Binding	Chemokine Receptor Activity C-C Chemokine Receptor Activity C-C Chemokine Binding
	Biological Process	Protein Retention In ER Lumen Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Transport T Cell Differentiation T Cell Apoptotic Process	CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Chemotaxis Immune Response Cellular Defense Response G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs			Vercirnon
Diseases
GWAS			Celiac disease ( 20190752) Liver enzyme levels (alkaline phosphatase) ( 33972514) Severe COVID-19 infection with respiratory failure (analysis I) ( 32558485) Severe COVID-19 infection with respiratory failure (analysis II) ( 32558485)
Interacting Genes		12 interacting genes: ARF1 ARFGAP1 CCR9 COPB1 DLG2 DLG3 F2RL1 GPR35 KRT34 LIG4 PRKACA SEC23B	20 interacting genes: ADGRG1 AIG1 CCL25 CD81 DGAT1 G6PC3 HLA-A KDELR1 NEU1 OSTC RHBDD2 SAP130 SCAMP4 SPNS1 TMC6 TMEM33 TRPM4 TSPAN7 TTYH1 YWHAE
Entrez ID		10945	10803
HPRD ID		00569	09200
Ensembl ID		ENSG00000105438	ENSG00000173585
Uniprot IDs		P24390	B2R734 P51686
PDB IDs			5LWE
Enriched GO Terms of Interacting Partners?
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