CERS1 and LTB4R2

Number of citations of the paper that reports this interaction (PubMedID 28298427)
23

Data Source:
BioGRID (two hybrid)

		CERS1	LTB4R2
Description		ceramide synthase 1	leukotriene B4 receptor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle	Nucleoplasm Plasma Membrane Integral Component Of Plasma Membrane Membrane
	Molecular Function	N-acyltransferase Activity Sphingosine N-acyltransferase Activity	Leukotriene B4 Receptor Activity Leukotriene Receptor Activity G Protein-coupled Peptide Receptor Activity
	Biological Process	Sphingolipid Biosynthetic Process Cellular Response To Mycotoxin Ceramide Biosynthetic Process Negative Regulation Of Telomerase Activity Cellular Response To Xenobiotic Stimulus Cellular Response To UV-A Cellular Response To Dithiothreitol Positive Regulation Of Mitophagy	Chemotaxis Inflammatory Response Negative Regulation Of Adenylate Cyclase Activity Neuropeptide Signaling Pathway Keratinocyte Migration Leukotriene Signaling Pathway
Pathways		Sphingolipid de novo biosynthesis	Leukotriene receptors G alpha (q) signalling events
Drugs			Amelubant Leukotriene B4
Diseases
GWAS			Anorectal malformation ( 31136621) Height ( 28552196)
Interacting Genes		5 interacting genes: BDKRB1 DRD2 HTR4 LTB4R2 MAPK6	48 interacting genes: AKT1 AP2M1 CANX CEBPZ CERS1 CHPT1 CNOT10 CRELD2 CSNK2B CTSA DDOST FOLR1 GJC2 GLOD4 GPR146 GPR37 HLA-A IL17RD IMP4 LAMP5 MDH1 MGLL MUC1 MYO1E OBSL1 P4HTM PER1 PIGM PKD1 PTGIS RPN2 SCARB1 SEC13 SGCB SLC2A1 STMN3 SV2A SYNGR2 TMED1 TMEM94 TMUB2 TSPAN3 TSPAN4 TSPAN7 TTC9B VPS25 WFS1 YIF1B
Entrez ID		10715	56413
HPRD ID		12114	16153
Ensembl ID		ENSG00000223802	ENSG00000213906
Uniprot IDs		B4DE47 P27544 Q5XG75	B4E292 Q9NPC1
PDB IDs
Enriched GO Terms of Interacting Partners?
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