EXOC5 and ICA1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
87

Data Source:
BioGRID (two hybrid)

		EXOC5	ICA1
Description		exocyst complex component 5	islet cell autoantigen 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Exocyst Cytoplasm Cytosol Midbody	Golgi Membrane Cytoplasm Golgi Apparatus Cytosol Secretory Granule Membrane Synaptic Vesicle Membrane Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding Small GTPase Binding Protein N-terminus Binding	Protein Binding Protein Domain Specific Binding Membrane Curvature Sensor Activity
	Biological Process	Establishment Of Planar Polarity Exocytosis Post-Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Transport Protein Transport Protein Localization To Plasma Membrane Epithelial Cell Apoptotic Process Non-motile Cilium Assembly	Neurotransmitter Transport Regulation Of Insulin Secretion Regulation Of Transport
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium
Drugs
Diseases
GWAS		Alcohol consumption ( 23743675) Chronotype ( 30696823) HDL cholesterol levels in HIV infection ( 33109212) Response to ranibizumab in age-related macular degeneration (exudative) ( 30054556)	Cognitive function ( 24684796) Intraocular pressure ( 23836780) Metabolite levels (Pyroglutamine) ( 23934736) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Systemic lupus erythematosus ( 28714469)
Interacting Genes		46 interacting genes: ACTR3B ADCK1 ARF6 BARD1 BRMS1L C1orf216 CCDC102B CDH2 CREBBP CRYBB1 DEUP1 DNAAF4 EDRF1 ENO2 EXOC6 EXOC6B FGA FRMD6 GNB1 HDDC3 HGS ICA1 IFT57 KIAA0586 KIFC3 KXD1 MAGEA3 MAGEA6 OAS1 PRKCG PSTPIP1 PTK6 PYCARD RAB14 RAB4A RAB4B RALA SOX10 SPACA9 TBX21 THOC1 TNPO2 TTC23L TXLNB TXNL4A USP2	8 interacting genes: CCDC28A EXOC5 ING5 MBD3 RAB2A RAB2B SHANK3 TSC1
Entrez ID		10640	3382
HPRD ID		07258	00971
Ensembl ID		ENSG00000070367	ENSG00000003147
Uniprot IDs		O00471	A0A024RA29 Q05084
PDB IDs
Enriched GO Terms of Interacting Partners?
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