SLU7 and PCBP2

Number of citations of the paper that reports this interaction (PubMedID 22365833)
163

Data Source:
BioGRID (two hybrid, two hybrid)

		SLU7	PCBP2
Description		SLU7 homolog, splicing factor	poly(rC) binding protein 2
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Cytosol Membrane Nuclear Speck Small Nuclear Ribonucleoprotein Complex Intracellular Membrane-bounded Organelle Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Cytoplasm Cytosol Focal Adhesion Membrane Extracellular Exosome
	Molecular Function	Second Spliceosomal Transesterification Activity Protein Binding Zinc Ion Binding Pre-mRNA 3'-splice Site Binding	Single-stranded DNA Binding RNA Binding MRNA Binding Protein Binding Enzyme Binding Ubiquitin Protein Ligase Binding
	Biological Process	RNA Splicing, Via Transesterification Reactions Alternative MRNA Splicing, Via Spliceosome MRNA 3'-splice Site Recognition MRNA Splicing, Via Spliceosome Intracellular Protein Transport RNA Splicing Cellular Response To Heat	Regulation Of Gene Expression MRNA Metabolic Process Viral RNA Genome Replication Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Innate Immune Response Negative Regulation Of Defense Response To Virus Regulation Of RNA Metabolic Process Defense Response To Virus IRES-dependent Viral Translational Initiation
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination	mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA Negative regulators of DDX58/IFIH1 signaling
Drugs
Diseases
GWAS		Asthma ( 32296059) Common carotid intima-media thickness ( 29206233)	Granulocyte percentage of myeloid white cells ( 27863252) Monocyte percentage of white cells ( 27863252) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		29 interacting genes: AIMP2 ARHGEF5 BAG2 CCDC85B CEP70 DEF6 FHL3 GOLGA2 GTF2I IKBKG JMJD6 KDM1A KRT40 LMNA LONRF1 LZTS2 MCC NFKBID NSD3 PCBP2 PIBF1 PPIG PPIL3 PRMT5 PRMT6 TEPSIN THAP1 ZBED8 ZCCHC10	30 interacting genes: BARD1 CASK CNBP FLNA FTH1 HMGA1 HMGA2 HNRNPD HNRNPK HNRNPL LINC01554 NKAP OGT PABPC1 PAXIP1 PC PCBP1 PRPF40A PTBP1 QKI SF3B2 SLU7 SNRPA SRSF3 SRSF7 UBC WDR77 WDR83 YBX1 YBX3
Entrez ID		10569	5094
HPRD ID		12074	03129
Ensembl ID		ENSG00000164609	ENSG00000197111
Uniprot IDs		O95391	A0A384N6B9 Q15366
PDB IDs		5XJC 6ICZ 6QDV	2AXY 2JZX 2P2R 2PQU 2PY9
Enriched GO Terms of Interacting Partners?
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