CXCL13 and PF4V1

Number of citations of the paper that reports this interaction (PubMedID 28381538)
37

Data Source:
BioGRID (pull down)

		CXCL13	PF4V1
Description		C-X-C motif chemokine ligand 13	platelet factor 4 variant 1
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GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Space
	Molecular Function	Chemokine Activity Heparin Binding Fibroblast Growth Factor Binding CXCR5 Chemokine Receptor Binding CCR10 Chemokine Receptor Binding CXCR Chemokine Receptor Binding Receptor Ligand Activity CXCR3 Chemokine Receptor Binding	Protein Binding Chemokine Activity Heparin Binding CXCR Chemokine Receptor Binding
	Biological Process	Germinal Center Formation Lymphocyte Chemotaxis Across High Endothelial Venule Chronic Inflammatory Response Regulation Of Humoral Immune Response Inflammatory Response Immune Response Cell Surface Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell-cell Signaling Positive Regulation Of T Cell Chemotaxis Neutrophil Chemotaxis Positive Regulation Of Integrin Activation Positive Regulation Of Cell-cell Adhesion Mediated By Integrin B Cell Chemotaxis Endothelial Cell Chemotaxis To Fibroblast Growth Factor Defense Response To Bacterium Regulation Of Angiogenesis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Activation Of GTPase Activity Negative Regulation Of Endothelial Cell Chemotaxis To Fibroblast Growth Factor	Inflammatory Response Platelet Activation Neutrophil Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Cellular Response To Lipopolysaccharide
Pathways		Chemokine receptors bind chemokines G alpha (i) signalling events	Common Pathway of Fibrin Clot Formation Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Cardiac Troponin-T levels ( 23247143) Diffusing capacity of carbon monoxide ( 30694715) Rheumatoid arthritis ( 32723749) Tonsillectomy ( 27182965 28928442) Waist circumference adjusted for body mass index ( 28552196)	Blood protein levels ( 29875488) Inflammatory bowel disease ( 23128233)
Interacting Genes		11 interacting genes: ACKR4 CCL19 CCL21 CCL28 CCL4L1 CCR10 CXCR3 CXCR5 EEF1G FGF2 PF4V1	15 interacting genes: CCL11 CCL19 CCL21 CCL22 CCL25 CCL26 CCL27 CCL28 CCL4L1 CXCL10 CXCL11 CXCL12 CXCL13 XCL1 XCL2
Entrez ID		10563	5197
HPRD ID		05513	01427
Ensembl ID		ENSG00000156234	ENSG00000109272
Uniprot IDs		O43927 Q53X90	P10720
PDB IDs		5CBA 5CBE 6VGJ 7JNY	4HSV
Enriched GO Terms of Interacting Partners?
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