APPBP2 and COL24A1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
484

Data Source:
BioGRID (two hybrid, two hybrid)

		APPBP2	COL24A1
Description		amyloid beta precursor protein binding protein 2	collagen type XXIV alpha 1 chain
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Microtubule Microtubule Associated Complex Cytoplasmic Vesicle Membrane Cul2-RING Ubiquitin Ligase Complex	Extracellular Region Collagen Trimer Extracellular Space Endoplasmic Reticulum Lumen Extracellular Matrix Collagen-containing Extracellular Matrix
	Molecular Function	Microtubule Motor Activity Protein Binding Ubiquitin Ligase-substrate Adaptor Activity	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength
	Biological Process	Intracellular Protein Transport Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Intracellular Transport	Extracellular Matrix Organization
Pathways			Collagen biosynthesis and modifying enzymes Assembly of collagen fibrils and other multimeric structures MET activates PTK2 signaling Collagen chain trimerization
Drugs
Diseases
GWAS		Interleukin-6 levels ( 33517400) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Waist-hip ratio ( 28552196)	Body shape index ( 34021172) Clozapine-induced agranulocytosis ( 25187353) Coronary artery aneurysm in Kawasaki disease ( 27171184) Hallux valgus ( 32131869) Intraocular pressure ( 29617998 29785010 31959993 30054594) Preterm birth (maternal effect) (maternal pre-pregnancy BMI interaction) ( 28598419) Reduced foot dorsiflexion strength in Charcot-Marie-Tooth disease type 1A ( 30706531) Urate levels in overweight individuals ( 25811787) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172)
Interacting Genes		120 interacting genes: - AADAC ACTN1 AHCY AIM2 AK3 ALDH1L1 ANKRD10 APP AR ARMCX5 ATP13A1 BCL7A BIN2 C1orf50 C6orf226 CALM3 CCDC167 CCDC85C CCNL1 CDK16 CHMP5 CIBAR1 CLCN1 CNTFR COL24A1 CORO2B CREB3 CSNK1G2 CST2 CTC1 CYBA DCD DHRS2 DHX16 DOLK DPEP1 DPYS EID3 ERO1A FAM107A FSTL1 FXYD7 GALNT3 GCSAM GP9 GPRC5C GSTP1 H2AC15 HGFAC HIPK4 HSD3B7 HSPA4 ITGB4 ITGB5 KHK KIF6 KLF11 KLHL35 LANCL2 LONRF3 LUC7L2 LUZP4 MAN2B2 MCOLN1 MFSD3 MGAT4B MLLT3 MMP28 MSH2 MSLN MUL1 MYLK NFYA NPRL3 PCSK5 PI4KAP2 PNPLA5 PPIL6 PPP1R8 PRKAA2 PRKACB PSAP PTCH1 PYROXD2 RAB7B RASSF5 RHEB RILPL1 RNF128 RNF34 RNGTT RRS1 SELENOI SELENOV SLC22A6 SLC25A23 SLC7A10 SLC9A3R1 SNX5 SPDYE2 SPDYE2B ST8SIA5 SYNRG SYT11 TAF11 TAFA4 TBL3 TCF25 TNP2 TRMT2A UBE2R2 UGGT2 WAS WDR24 WFIKKN1 WNT5B ZC3H10 ZCCHC12 ZNF747	1 interacting genes: APPBP2
Entrez ID		10513	255631
HPRD ID		05616	10846
Ensembl ID		ENSG00000062725	ENSG00000171502
Uniprot IDs		A0A024QZ47 Q92624	F8WDM8 Q17RW2
PDB IDs
Enriched GO Terms of Interacting Partners?
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