ZNHIT1 and MYO5B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ZNHIT1	MYO5B
Description		zinc finger HIT-type containing 1	myosin VB
Image		No pdb structure
GO Annotations	Cellular Component	Swr1 Complex Nucleus Nucleoplasm	Cytoplasm Actin Cytoskeleton Myosin Complex Cytoplasmic Vesicle Membrane Vesicle Protein-containing Complex Apical Cortex Recycling Endosome Extracellular Exosome
	Molecular Function	Protein Binding Nucleosome Binding Metal Ion Binding	Microfilament Motor Activity Protein Binding Calmodulin Binding ATP Binding Small GTPase Binding Actin Filament Binding
	Biological Process	Histone Exchange	Renal Water Homeostasis Actin Filament Organization Protein Transport Vesicle-mediated Transport Endosomal Transport Vesicle Transport Along Actin Filament
Pathways			Vasopressin regulates renal water homeostasis via Aquaporins
Drugs
Diseases
GWAS			Apolipoprotein A1 levels ( 32203549 29084231) HDL cholesterol levels ( 32203549) Large HDL particle concentration ( 29084231) Mean diameter of HDL particles ( 29084231) Medium HDL particle concentration ( 29084231) Multiple sclerosis ( 31604244) Myopia ( 27182965) Phospholipid levels in large HDL ( 29084231) Phospholipid levels in medium HDL ( 29084231) Refractive error ( 32231278) Resistant hypertension ( 31545351) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systolic blood pressure x smoking status (current vs non-current) interaction (1df test) ( 29455858) Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858) Total cholesterol levels in HDL ( 29084231)
Interacting Genes		25 interacting genes: AKAP8 BCL6 COL8A1 CSNK2B CYSRT1 DAPP1 FHL5 GOLGA6L9 GRB7 HINFP KANK2 KRTAP10-6 KRTAP10-7 KRTAP12-2 MAPK11 MAPK14 MAPK9 MDFI MYO5B OTX2 PMPCB RIPK1 SH2D1A TNIP1 TP53	23 interacting genes: AMOTL2 BNIP2 COIL CXCR2 EFHC2 FAM214B FXR1 GMCL1 KIAA1549 MEI4 MEOX2 POLR1C RAB11A RAB11B RAB11FIP2 RAB25 SHANK3 SMAD3 SMARCA2 TCF4 TRIM3 TRIM54 ZNHIT1
Entrez ID		10467	4645
HPRD ID		15892	07582
Ensembl ID		ENSG00000106400	ENSG00000167306
Uniprot IDs		O43257	Q7Z7A5 Q9ULV0
PDB IDs			4J5M 4LNZ 4LWZ 4LX0
Enriched GO Terms of Interacting Partners?
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