TAB1 and XPO7

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		TAB1	XPO7
Description		TGF-beta activated kinase 1 (MAP3K7) binding protein 1	exportin 7
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Endosome Membrane Nuclear Speck Protein-containing Complex	Nucleus Nuclear Pore Cytoplasm
	Molecular Function	Protein Binding Enzyme Activator Activity Phosphatase Activity Kinase Activator Activity Protein-containing Complex Binding Mitogen-activated Protein Kinase P38 Binding	Nuclear Export Signal Receptor Activity Protein Binding Small GTPase Binding
	Biological Process	In Utero Embryonic Development Heart Morphogenesis Cardiac Septum Development Negative Regulation Of Protein Kinase Activity Protein Dephosphorylation Transforming Growth Factor Beta Receptor Signaling Pathway Lung Development Aorta Development Positive Regulation Of MAP Kinase Activity Coronary Vasculature Development	Protein Export From Nucleus
Pathways		NOD1/2 Signaling Pathway FCERI mediated NF-kB activation TAK1 activates NFkB by phosphorylation and activation of IKKs complex activated TAK1 mediates p38 MAPK activation JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 TNFR1-induced NFkappaB signaling pathway CLEC7A (Dectin-1) signaling Ub-specific processing proteases TICAM1,TRAF6-dependent induction of TAK1 complex Interleukin-1 signaling IRAK2 mediated activation of TAK1 complex TRAF6-mediated induction of TAK1 complex within TLR4 complex Alpha-protein kinase 1 signaling pathway IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
Drugs		Manganese
Diseases
GWAS		Factor VIII levels ( 30586737) IgG bisecting N-acetyl glucosamine phenotypes (multivariate analysis) ( 28878392) IgG digalactosylation phenotypes (multivariate analysis) ( 28878392) IgG disialylation phenotypes (multivariate analysis) ( 28878392) IgG fucosylation phenotypes (multivariate analysis) ( 28878392) IgG galactosylation phenotypes (multivariate analysis) ( 28878392) IgG glycosylation ( 23382691) IgG monogalactosylation phenotypes (multivariate analysis) ( 28878392) IgG N-glycosylation phenotypes (multivariate analysis) ( 28878392) IgG sialylation phenotypes (multivariate analysis) ( 28878392) Inflammatory bowel disease ( 23128233) Intelligence (MTAG) ( 29326435) Schizophrenia ( 29483656) Serum alkaline phosphatase levels ( 33547301) Sleep duration (short sleep) ( 30846698) vWF levels ( 30586737) Waist circumference ( 28552196)	Atrial fibrillation ( 30061737 29892015) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Lung cancer in ever smokers ( 28604730) Maximum habitual alcohol consumption ( 31151762) Mean corpuscular hemoglobin ( 29403010 32888494 27863252 28017375) Mean corpuscular volume ( 29403010 32888494 20139978 27863252) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Metabolite levels ( 23823483) Platelet distribution width ( 32888494) PR interval ( 32439900) Red blood cell count ( 32888494 27863252) Refractive error ( 32231278)
Interacting Genes		79 interacting genes: AATK ACAP3 ARAP1 ASRGL1 BMPR1A C9orf78 CARD11 CASP6 CDK5RAP3 CFL1 CKB CORO1A CXCL16 DBN1 DVL2 EGFR EPRS1 ERBB4 FADD FN1 GIT1 HMGXB4 HNRNPR IFT27 IKBKG ITCH KDELR3 KIFC2 LAP3 LCMT1 LGALS7 LGALS7B LNX2 MAP3K1 MAP3K7 MAPK11 MAPK14 MAPKAPK5 MICAL1 MON1A MTG2 NR2C2 NXPH3 OGT PDCD6IP PHACTR3 PHC2 POLDIP2 POLR3D PPP1R7 PPP2CB PPP2R1A PRKAR1A PTPMT1 RBX1 ROR2 RPL10 RPLP1 SERPINA4 SMAD6 SMAD7 SMURF1 SNRNP35 TAB2 TAB3 TOM1 TRAF2 TRAF6 TRIP6 TRPC4AP TSSC4 UBC URB1 WDCP WTAP XIAP XPO7 YWHAG ZMYND11	9 interacting genes: ATXN1 DDX19B MAPK9 NUP153 PDPK1 RAN TAB1 USO1 XPOT
Entrez ID		10454	23039
HPRD ID		04012	05846
Ensembl ID		ENSG00000100324	ENSG00000130227
Uniprot IDs		A8K6K3 Q15750	Q9UIA9
PDB IDs		2J4O 2POM 2POP 2YDS 2YIY 4AY5 4AY6 4GS6 4KA3 4L3P 4L52 4L53 4O91 5DIY 5E7R 5GJD 5GJF 5GJG 5J7S 5J8I 5J9L 5JGA 5JGB 5JGD 5JH6 5JK3 5NZZ 5O90 5V5N 5VVU
Enriched GO Terms of Interacting Partners?
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