FAM3C and GGT6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		FAM3C	GGT6
Description		FAM3 metabolism regulating signaling molecule C	gamma-glutamyltransferase 6
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Golgi Apparatus Platelet Dense Granule Lumen Extracellular Exosome	Integral Component Of Membrane Extracellular Exosome
	Molecular Function	Cytokine Activity Protein Binding	Molecular_function Protein Binding Glutathione Hydrolase Activity Hypoglycin A Gamma-glutamyl Transpeptidase Activity Leukotriene C4 Gamma-glutamyl Transferase Activity
	Biological Process	Signal Transduction Biological_process Negative Regulation Of Gluconeogenesis	Proteolysis Glutathione Biosynthetic Process Biological_process Leukotriene D4 Biosynthetic Process
Pathways		Platelet degranulation	Glutathione synthesis and recycling Aflatoxin activation and detoxification
Drugs
Diseases
GWAS		Biomedical quantitative traits ( 19396169) Bone mineral density (paediatric, lower limb) ( 24945404) Bone mineral density (paediatric, skull) ( 24945404) Bone mineral density (paediatric, total body less head) ( 24945404) Bone mineral density (paediatric, upper limb) ( 24945404) Calcaneus stiffness index ( 30779856) Forearm bone mineral density ( 26367794) Hand grip strength ( 27325353) Heel bone mineral density ( 30598549 28869591) Lung adenocarcinoma ( 28604730) Pediatric bone mineral content (radius) ( 26041818) Phenylephrine infusion rate during anesthesia ( 31455332) Total body bone mineral density ( 30172743) Ulna and radius bone mineral density ( 30172743)	Rheumatoid arthritis ( 28118524) Rheumatoid arthritis (rheumatoid factor and/or anti-cyclic citrullinated peptide seropositive) ( 28118524)
Interacting Genes		48 interacting genes: AHNAK2 BIK BNIP2 CLEC17A CLEC2D CLEC4E CREB3 CREB3L1 CXADR CYB5R3 ELOVL4 ERGIC3 EVI2B FAM209A FCGR1A FCGRT FFAR2 FKBP7 GGT6 GJB5 GPR42 GPX8 HHLA2 KCNA2 KIR2DL3 LMNA LRRC25 MFF PDZK1IP1 RELL2 RMDN3 RNASEH1 SAR1A SCN3B SLC10A6 SLC16A2 SLC18A1 SLC35C2 SPINT1 SSMEM1 STX1A TEX29 TMEM248 TMEM45B TMEM71 TMEM80 TMPRSS2 TMX2	11 interacting genes: ADAM33 BMP10 ENTPD3 FAIM2 FAM3C GRINA NOTCH3 PIGS SEC22A TMBIM1 TNMD
Entrez ID		10447	124975
HPRD ID		12270	08293
Ensembl ID		ENSG00000196937	ENSG00000167741
Uniprot IDs		Q92520	B4DKN3 J3KPJ0 Q6P531 Q6ZPD7
PDB IDs		5LC2
Enriched GO Terms of Interacting Partners?
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