CDC42EP2 and SEPTIN6

Number of citations of the paper that reports this interaction (PubMedID 11584266)
78

Data Source:
BioGRID (pull down)

		CDC42EP2	SEPTIN6
Description		CDC42 effector protein 2	septin 6
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Endomembrane System Microtubule Cytoskeleton Membrane Phagocytic Vesicle	Kinetochore Spindle Septin Ring Synaptic Vesicle Microtubule Cytoskeleton Midbody Septin Complex Cell Division Site Cleavage Furrow Septin Collar Axon Terminus Sperm Annulus
	Molecular Function	Opioid Peptide Activity GTPase Activator Activity Protein Binding Small GTPase Binding	GTPase Activity Protein Binding GTP Binding Molecular Adaptor Activity
	Biological Process	Actin Filament Organization Rho Protein Signal Transduction Regulation Of Cell Shape Actin Cytoskeleton Organization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Pseudopodium Assembly Positive Regulation Of Protein-containing Complex Assembly Regulation Of Catalytic Activity Cellular Response To Interferon-gamma	Mitotic Cytokinesis Spermatogenesis Cell Differentiation Cellular Protein Localization Cilium Assembly Cytoskeleton-dependent Cytokinesis
Pathways		MAPK6/MAPK4 signaling CDC42 GTPase cycle RHOQ GTPase cycle
Drugs
Diseases
GWAS		Acne (severe) ( 24927181) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494 27863252)
Interacting Genes		11 interacting genes: ARHGAP26 CASS4 CDC42 COX5B NEDD9 NME7 PICK1 RHOQ SEPTIN6 SEPTIN7 SNCA	14 interacting genes: CDC42EP2 CDC42EP3 CRK KDM1A MORN4 NSD3 PLEKHF2 RHOU S100A4 SEPTIN1 SEPTIN2 SEPTIN9 SH3KBP1 TK1
Entrez ID		10435	23157
HPRD ID		09363	06716
Ensembl ID		ENSG00000149798	ENSG00000125354
Uniprot IDs		O14613	B1AMS2 Q14141 Q541S4 Q548C9
PDB IDs			2QAG 6UPA
Enriched GO Terms of Interacting Partners?
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