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TUBB4A and SBNO2
TUBB4A
SBNO2
Description
tubulin beta 4A class IVa
strawberry notch homolog 2
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Microtubule
Axoneme
Internode Region Of Axon
Neuronal Cell Body
Myelin Sheath
Extracellular Exosome
Cellular_component
Nucleus
Molecular Function
GTPase Activity
Structural Constituent Of Cytoskeleton
Calcium Ion Binding
Protein Binding
GTP Binding
Chromatin DNA Binding
Histone Binding
Biological Process
Microtubule Cytoskeleton Organization
Mitotic Cell Cycle
Negative Regulation Of Microtubule Polymerization
Macrophage Activation Involved In Immune Response
Regulation Of Transcription, DNA-templated
Bone Mineralization
Osteoclast Differentiation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Regulation Of Inflammatory Response
Bone Trabecula Morphogenesis
Cellular Response To Lipopolysaccharide
Cellular Response To Interleukin-11
Cellular Response To Interleukin-6
Osteoclast Fusion
Cellular Response To Leukemia Inhibitory Factor
Pathways
Translocation of SLC2A4 (GLUT4) to the plasma membrane
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
Gap junction assembly
MHC class II antigen presentation
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
Regulation of PLK1 Activity at G2/M Transition
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Prefoldin mediated transfer of substrate to CCT/TriC
Formation of tubulin folding intermediates by CCT/TriC
Post-chaperonin tubulin folding pathway
Recycling pathway of L1
Recycling pathway of L1
Hedgehog 'off' state
Cilium Assembly
Anchoring of the basal body to the plasma membrane
Intraflagellar transport
RHO GTPases activate IQGAPs
RHO GTPases Activate Formins
COPI-mediated anterograde transport
COPI-dependent Golgi-to-ER retrograde traffic
COPI-independent Golgi-to-ER retrograde traffic
Mitotic Prometaphase
The role of GTSE1 in G2/M progression after G2 checkpoint
AURKA Activation by TPX2
Carboxyterminal post-translational modifications of tubulin
Carboxyterminal post-translational modifications of tubulin
HCMV Early Events
Assembly and cell surface presentation of NMDA receptors
Activation of AMPK downstream of NMDARs
Aggrephagy
Aggrephagy
EML4 and NUDC in mitotic spindle formation
Sealing of the nuclear envelope (NE) by ESCRT-III
Kinesins
Drugs
Epothilone D
Patupilone
CYT997
ZEN-012
Artenimol
Diseases
GWAS
Left-handedness (
32989287
)
Left–right brain asymmetry (
33723403
)
Asthma (childhood onset) (
31036433
30929738
)
Asthma onset (childhood vs adult) (
30929738
)
Basal cell carcinoma (
33549134
)
Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) (
26974007
)
Crohn's disease (
28067908
21102463
)
Distal/Left-sided colorectal cancer (
33632709
)
Eosinophil percentage of white cells (
32888494
)
Heel bone mineral density (
30598549
28869591
)
High light scatter reticulocyte count (
32888494
27863252
)
High light scatter reticulocyte percentage of red cells (
32888494
27863252
)
Immature fraction of reticulocytes (
32888494
27863252
)
Inflammatory bowel disease (
28067908
)
Lymphocyte counts (
32888494
)
Lymphocyte percentage of white cells (
32888494
)
Mean reticulocyte volume (
32888494
)
Medication use (thyroid preparations) (
31015401
)
Reticulocyte count (
32888494
27863252
)
Reticulocyte fraction of red cells (
32888494
27863252
)
Systemic lupus erythematosus (
28714469
)
White blood cell count (
29403010
)
Interacting Genes
18 interacting genes:
ABCA7
APC2
BMPR2
CLN8
HMG20B
KDM4B
LINC01554
NEAT1
NR4A1
OGT
PLIN3
SBNO2
SELENOF
STAU1
STK11
SUMO2
UQCR11
YWHAG
1 interacting genes:
TUBB4A
Entrez ID
10382
22904
HPRD ID
04045
17203
Ensembl ID
ENSG00000104833
ENSG00000064932
Uniprot IDs
P04350
Q9Y2G9
PDB IDs
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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