KATNB1 and KATNA1

Number of citations of the paper that reports this interaction (PubMedID 10751153)
61

Data Source:
HPRD (in vivo, in vitro)

		KATNB1	KATNA1
Description		katanin regulatory subunit B1	katanin catalytic subunit A1
Image		No pdb structure
GO Annotations	Cellular Component	Spindle Pole Nucleus Cytoplasm Centrosome Spindle Cytosol Microtubule Plasma Membrane Katanin Complex Microtubule Cytoskeleton Membrane Growth Cone Midbody Neuronal Cell Body	Spindle Pole Cytoplasm Centrosome Spindle Microtubule Microtubule Cytoskeleton Midbody Mitotic Spindle Pole
	Molecular Function	Protein Binding Microtubule Binding Protein Heterodimerization Activity ATPase Regulator Activity Dynein Complex Binding	Protein Binding ATP Binding Microtubule Binding Microtubule-severing ATPase Activity Isomerase Activity Protein Heterodimerization Activity
	Biological Process	Protein Targeting Microtubule Depolymerization Negative Regulation Of Microtubule Depolymerization Mitotic Chromosome Movement Towards Spindle Pole Positive Regulation Of Cell Death Positive Regulation Of Neuron Projection Development Positive Regulation Of Microtubule Depolymerization Regulation Of Catalytic Activity Microtubule Severing Cell Division	Cell Cycle Microtubule Severing Cell Division
Pathways
Drugs
Diseases
GWAS			Brain morphology (MOSTest) ( 32665545) Lung cancer ( 27393504) Subcortical volume (MOSTest) ( 32665545) Testicular germ cell tumor ( 28604728)
Interacting Genes		6 interacting genes: DYNC1H1 KATNA1 PAFAH1B1 RXFP3 TGFBR1 XRN1	11 interacting genes: APP CLK1 CLU DCAF1 DYNC1H1 DYRK2 ESR1 KATNB1 LIPE OGT PAFAH1B1
Entrez ID		10300	11104
HPRD ID		04081	05986
Ensembl ID		ENSG00000140854	ENSG00000186625
Uniprot IDs		Q9BVA0	A8K7S5 O75449
PDB IDs			5ZQL 5ZQM
Enriched GO Terms of Interacting Partners?
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