RABEPK and PRKRA

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		RABEPK	PRKRA
Description		Rab9 effector protein with kelch motifs	protein activator of interferon induced protein kinase EIF2AK2
Image		No pdb structure
GO Annotations	Cellular Component	Endosome Cytosol Endosome Membrane Transport Vesicle Trans-Golgi Network Membrane	Nucleoplasm Cytoplasm Cytosol Membrane Perinuclear Region Of Cytoplasm RISC-loading Complex
	Molecular Function	Protein Binding	RNA Binding Double-stranded RNA Binding Protein Binding Enzyme Activator Activity Enzyme Binding Identical Protein Binding Protein Homodimerization Activity Pre-miRNA Binding
	Biological Process	Receptor-mediated Endocytosis Vesicle Docking Involved In Exocytosis	Protein Phosphorylation Immune Response Negative Regulation Of Cell Population Proliferation Response To Virus Production Of SiRNA Involved In RNA Interference Pre-miRNA Processing Cellular Response To Oxidative Stress Production Of MiRNAs Involved In Gene Silencing By MiRNA Outer Ear Morphogenesis Middle Ear Morphogenesis Skeletal System Morphogenesis Regulation Of Catalytic Activity Protein Stabilization Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Retrograde transport at the Trans-Golgi-Network	MicroRNA (miRNA) biogenesis Small interfering RNA (siRNA) biogenesis
Drugs
Diseases
GWAS		Refractive error ( 32231278)	Inflammatory skin disease ( 25574825) Multiple sclerosis (OCB status) ( 23472185) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183)
Interacting Genes		8 interacting genes: GLUL PIKFYVE POR PRKRA RAB9A TMEM98 TRIM55 ZYX	34 interacting genes: ADARB1 AGO2 CAT CEBPZ CEP126 CLASP1 COPS6 DICER1 EHHADH EIF2AK2 FZD7 GDF9 HEYL LNX1 LYAR NKRF PIAS2 PITPNM1 PLEKHA3 POLR2G RABEPK RB1 SETDB1 SHC1 SNX5 STAU1 STRBP TARBP2 TIRAP TP53 ZFP28 ZMAT3 ZMAT4 ZNF746
Entrez ID		10244	8575
HPRD ID		09337	04573
Ensembl ID		ENSG00000136933	ENSG00000180228
Uniprot IDs		A0A024R8A0 A0A0S2Z4Z1 A0A0S2Z4Z5 Q7Z6M1	A0A7I2V2I8 B4DJC7 O75569
PDB IDs			2DIX
Enriched GO Terms of Interacting Partners?
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