CALCOCO2 and MYH6

Number of citations of the paper that reports this interaction (PubMedID 29187741)
11

Data Source:
BioGRID (pull down)

		CALCOCO2	MYH6
Description		calcium binding and coiled-coil domain 2	myosin heavy chain 6
Image			No pdb structure
GO Annotations	Cellular Component	Autophagosome Membrane Nucleus Cytoplasm Autophagosome Cytosol Cytoskeleton Membrane PML Body Cytoplasmic Vesicle Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Stress Fiber Cytosol Muscle Myosin Complex Myosin Complex Myofibril Sarcomere Z Disc Myosin Filament
	Molecular Function	Protein Binding Protein Homodimerization Activity Metal Ion Binding	Microfilament Motor Activity Calmodulin Binding ATP Binding Myosin Phosphatase Activity Protein Kinase Binding Actin Filament Binding
	Biological Process	Viral Process Response To Interferon-gamma Xenophagy Positive Regulation Of Autophagosome Maturation	In Utero Embryonic Development Regulation Of The Force Of Heart Contraction Regulation Of Heart Rate Protein Dephosphorylation Muscle Contraction Striated Muscle Contraction Adult Heart Development Visceral Muscle Development Regulation Of Heart Contraction Regulation Of Blood Pressure Cardiac Muscle Hypertrophy In Response To Stress Muscle Filament Sliding Myofibril Assembly Regulation Of ATPase Activity Sarcomere Organization ATP Metabolic Process Atrial Cardiac Muscle Tissue Morphogenesis Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Cell Development Cardiac Muscle Contraction Regulation Of Heart Growth
Pathways			Striated Muscle Contraction
Drugs
Diseases
GWAS		Blood protein levels ( 30072576) Chronotype ( 30696823) Liver enzyme levels (alkaline phosphatase) ( 33972514) Serum alkaline phosphatase levels ( 33547301) Type 2 diabetes ( 29358691 29632382) Type 2 diabetes (adjusted for BMI) ( 29632382)	Aortic coarctation ( 29590334) Atrial fibrillation ( 30061737) Diastolic blood pressure ( 30578418) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Electrocardiographic traits ( 20062063) Electrocardiographic traits (multivariate) ( 32602732) Heart rate ( 23583979) P wave duration ( 28794112) P wave terminal force ( 28794112) PR interval ( 30046033 32439900) Pulse pressure ( 28135244 27618447 27618448 30578418) Resting heart rate ( 29769521 23183192 27798624 28270201 20639392) RR interval (heart rate) ( 30679814) Systolic blood pressure ( 27618447)
Interacting Genes		183 interacting genes: ABLIM1 ADSL AKAP17A AMMECR1 AP5B1 APEX2 ARHGEF39 ARHGEF5 ARNT2 ATG5 AXIN1 BAHD1 BCL6B BEX2 CBX8 CCDC120 CCDC185 CCDC33 CCNH CDC7 CELA2B CEP57L1 CHCHD3 CNNM3 CPNE7 CWF19L2 DAXX DAZAP2 DBNDD2 DCTN4 DCX DDIT4L DDX6 DOCK2 DUSP12 DUSP26 EEF1E1 EFHC1 ELOA2 ENKD1 EXOSC5 FAM107A FAM161A FAM168A FAM189A2 FAM214B FAM90A1 FARS2 FASTK FBF1 FBXL18 FKBPL FMR1 FNDC11 FOXD4L3 FXR2 GABARAPL1 GABARAPL2 GATAD2B GCA GEMIN4 GIT2 GLYCTK HDAC4 HDAC7 HLX HNRNPLL HOXB5 HOXB9 IKBKG IL16 IQUB KANSL1 KAT7 KLHL35 KLHL42 LENG1 LGALS8 LGALS9 LIMS2 LITAF LMF2 LMO2 LMO4 LNX1 LONRF1 LSM4 MAGOHB MAP1LC3C MCM10 METTL17 MID2 MOS MTPAP MVP MXI1 MYH6 MYO6 NAA10 NDN NFU1 ORC5 PCGF1 PEF1 PEG10 PFDN5 PHF1 PIAS4 PLEKHN1 POLI POLR2A PPP1R18 PRKAA2 PRKAB2 PRPF18 PRPF31 PSMA1 PSME4 PTBP1 PTBP2 QARS1 RAB35 RABL6 RBM15 RHPN1 RIN1 RNF11 RPA2 RPL9 RPS27A RTN4IP1 RTP5 RXRB SCAND1 SCNM1 SDCBP SETD5 SHC1 SLC15A3 SMARCD1 SMCP SNRPB SPATA24 SRI STAMBPL1 STK16 TACO1 TBC1D22B TBK1 TBKBP1 TBRG4 TCL1A TEKT3 TENT2 TLE5 TP53RK TRAF2 TRAF4 TRAF6 TSC1 TSGA10IP TTC23L UBAC2 USP2 VARS1 VPS72 ZBTB4 ZC2HC1C ZNF101 ZNF205 ZNF337 ZNF408 ZNF414 ZNF426 ZNF451 ZNF564 ZNF581 ZNF638 ZNF648 ZNF688 ZNF696 ZNF774 ZNF80	6 interacting genes: CALCOCO1 CALCOCO2 ESR1 HSPB2 POLR2A TRIM63
Entrez ID		10241	4624
HPRD ID		06846	01171
Ensembl ID		ENSG00000136436	ENSG00000197616
Uniprot IDs		Q13137	P13533
PDB IDs		2MXP 3VVV 3VVW 4GXL 4HAN 4XKL 5AAQ 5Z7A 5Z7L
Enriched GO Terms of Interacting Partners?
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