PLIN3 and TARS2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		PLIN3	TARS2
Description		perilipin 3	threonyl-tRNA synthetase 2, mitochondrial
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endosome Golgi Apparatus Lipid Droplet Cytosol Endosome Membrane Membrane Transport Vesicle	Cellular_component Mitochondrial Matrix
	Molecular Function	Protein Binding Cadherin Binding	Aminoacyl-tRNA Editing Activity Threonine-tRNA Ligase Activity Protein Binding ATP Binding Protein Homodimerization Activity
	Biological Process	Positive Regulation Of Sequestering Of Triglyceride Vesicle-mediated Transport Lipid Storage	Threonyl-tRNA Aminoacylation Mitochondrial Threonyl-tRNA Aminoacylation Aminoacyl-tRNA Metabolism Involved In Translational Fidelity
Pathways		Triglyceride catabolism Retrograde transport at the Trans-Golgi-Network Lipophagy Chaperone Mediated Autophagy Late endosomal microautophagy RHOBTB3 ATPase cycle	Mitochondrial tRNA aminoacylation
Drugs		Idursulfase Galsulfase	Threonine
Diseases
GWAS		Basal cell carcinoma ( 27539887) Lung cancer in ever smokers ( 28604730) Visceral fat ( 30942860)	Alanine aminotransferase levels ( 33547301) Blood protein levels ( 28240269) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Chronotype ( 30696823 27494321) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) LDL cholesterol levels ( 32203549) Liver enzyme levels (alanine transaminase) ( 33972514) Morning person ( 30696823) Morning vs. evening chronotype ( 27494321) Plateletcrit ( 32888494) Refractive error ( 32231278) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		33 interacting genes: ABHD4 ABHD5 APP CCNC CHMP4B CMTM5 CPD CYBC1 GAD2 HSD17B13 IGF2R LNPK M6PR MAX MIEF1 MYG1 PBX3 PIAS3 PTPN9 RAB9A SFT2D2 SMAD2 SNX1 SNX2 SPART SYNGR1 SYNGR3 SYP TARS2 TBC1D13 TBPL1 TMEM14C TUBB4A	15 interacting genes: ANP32E ARL6IP1 ASB6 CIART FKBP7 GABPB2 H3C14 HOMEZ PLIN3 SLC17A9 SYPL1 TARS3 TNFAIP8L2 TNFRSF10D ZNF687
Entrez ID		10226	80222
HPRD ID		04080	18148
Ensembl ID		ENSG00000105355	ENSG00000143374
Uniprot IDs		A0A140VJN8 O60664	Q9BW92 U3KQG0
PDB IDs
Enriched GO Terms of Interacting Partners?
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