TRIM13 and ARHGDIA

Number of citations of the paper that reports this interaction (PubMedID 21900206)
136

Data Source:
BioGRID (two hybrid)

		TRIM13	ARHGDIA
Description		tripartite motif containing 13	Rho GDP dissociation inhibitor alpha
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Endoplasmic Reticulum Membrane Integral Component Of Membrane Endoplasmic Reticulum Quality Control Compartment Perinuclear Endoplasmic Reticulum	Immunological Synapse Nucleus Cytosol Cytoskeleton Membrane Synapse Extracellular Exosome
	Molecular Function	Transcription Coactivator Activity Ubiquitin-protein Transferase Activity Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Activity	Rho GDP-dissociation Inhibitor Activity GTPase Activator Activity Fatty Acid Binding Protein Binding Protein Kinase Binding Small GTPase Binding Hsp90 Protein Binding
	Biological Process	Anatomical Structure Morphogenesis Response To Gamma Radiation Positive Regulation Of Cell Death Positive Regulation Of Macroautophagy Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Negative Regulation Of Viral Transcription Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Innate Immune Response Positive Regulation Of Transcription, DNA-templated Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Autoubiquitination Negative Regulation Of Viral Release From Host Cell Endoplasmic Reticulum Mannose Trimming	Negative Regulation Of Cell Adhesion Rho Protein Signal Transduction Regulation Of Cell Shape Negative Regulation Of Cell Migration Regulation Of Protein Localization Regulation Of Rho Protein Signal Transduction Negative Regulation Of Apoptotic Process Regulation Of Catalytic Activity Cellular Response To Mechanical Stimulus Cellular Response To Organic Cyclic Compound Cellular Response To Redox State Semaphorin-plexin Signaling Pathway Regulation Of Actin Cytoskeleton Reorganization
Pathways		ER Quality Control Compartment (ERQC)	Axonal growth inhibition (RHOA activation) Axonal growth stimulation RHOA GTPase cycle RHOC GTPase cycle CDC42 GTPase cycle RAC1 GTPase cycle RAC2 GTPase cycle RHOH GTPase cycle RHOG GTPase cycle
Drugs		Etorphine Diprenorphine Dihydromorphine
Diseases
GWAS		Diastolic blood pressure ( 30224653) Height ( 23563607) Hip circumference adjusted for BMI ( 34021172) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		6 interacting genes: AKT1 ARHGDIA GMCL1 MDM2 ROBO2 UBE2D2	41 interacting genes: ACTL6A ADRB2 ATXN3 BAK1 CASP3 CASP7 CBX5 CDC42 CDKN1B EP300 FEN1 HAAO HDAC6 HERPUD1 IKBKG JUP KAT2B MAPK6 NEDD4L POT1 RAC1 RAC2 RAC3 RDX RHOA RHOG RHOH SDHC SH3GL3 SIRT2 ST3GAL4 SUMO4 TERF1 TINF2 TRIM13 TWF2 UBE2I UBE2L6 UBE2R2 UFM1 VAV1
Entrez ID		10206	396
HPRD ID		10414	03565
Ensembl ID		ENSG00000204977	ENSG00000141522
Uniprot IDs		A0A024RDU3 L7MTJ6 O60858	J3QQX2 P52565 V9HWE8
PDB IDs			1CC0 1FSO 1FST 1FT0 1FT3 1HH4 1KMT 1QVY 1RHO 2BXW 2JHS 2JHT 2JHU 2JHV 2JHW 2JHX 2JHY 2JHZ 2JI0 2N80
Enriched GO Terms of Interacting Partners?
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