MPHOSPH6 and EIF3G

Number of citations of the paper that reports this interaction (PubMedID 15231747)
57

Data Source:
HPRD (two hybrid)

		MPHOSPH6	EIF3G
Description		M-phase phosphoprotein 6	eukaryotic translation initiation factor 3 subunit G
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GO Annotations	Cellular Component	Exosome (RNase Complex) Nucleus Nucleoplasm Nucleolus Cytosol	Nucleus Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Protein Binding	RNA Binding Translation Initiation Factor Activity Protein Binding
	Biological Process	Maturation Of 5.8S RRNA	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation Viral Translational Termination-reinitiation
Pathways		Major pathway of rRNA processing in the nucleolus and cytosol	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Leukocyte telomere length ( 32109421 31171785) Lung adenocarcinoma ( 28604730) Nevus count or cutaneous melanoma ( 32341527) Obesity-related traits ( 23251661) Parkinson's disease motor subtype (tremor dominant vs postural instability/gait difficulty) ( 33987465) Seasonality and depression ( 30217971)
Interacting Genes		30 interacting genes: AATF APLP1 ARHGAP18 DNM2 DYNLRB1 EIF3G ERG28 EXOSC10 EXOSC3 EXOSC5 EXOSC7 EXOSC8 FTL GDF9 HSBP1 HSPB1 KNSTRN LRIF1 MTREX NUPR1 PARN RBM48 RPS20 SMARCA4 SNX9 THOP1 TLE1 TP53 UNC119 ZHX1	29 interacting genes: ACD AIFM1 APP EIF3A EIF3B EIF3C EIF3D EIF3H EIF3K EIF5 EPB41 FAM9B GADD45G GOLGA2 LMNA MEOX2 METTL3 MIF4GD MPHOSPH6 OGT PALS2 PIN1 PKN2 POT1 PRKAG1 SMN1 SNCA TK1 TRIM14
Entrez ID		10200	8666
HPRD ID		16111	04886
Ensembl ID		ENSG00000135698	ENSG00000130811
Uniprot IDs		H3BNT4 Q99547	O75821
PDB IDs		6D6Q 6D6R 6H25	2CQ0 2MJC 5K0Y 6YBS 6ZMW
Enriched GO Terms of Interacting Partners?
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