MPHOSPH9 and SVIL

Number of citations of the paper that reports this interaction (PubMedID 20309963)
28

Data Source:
BioGRID (two hybrid)

		MPHOSPH9	SVIL
Description		M-phase phosphoprotein 9	supervillin
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Centriole Membrane	Podosome Nucleus Cytoplasm Cytosol Plasma Membrane Focal Adhesion Actin Cytoskeleton Midbody Cleavage Furrow Microtubule Minus-end Cell Projection Costamere
	Molecular Function		Protein Binding Phosphatidylinositol-4,5-bisphosphate Binding Actin Filament Binding
	Biological Process		Skeletal Muscle Tissue Development Actin Polymerization Or Depolymerization Positive Regulation Of Cytokinesis Actin Filament Severing Barbed-end Actin Filament Capping
Pathways
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Autism spectrum disorder or schizophrenia ( 28540026) Body shape index ( 34021172) Brain morphology (MOSTest) ( 32665545) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Educational attainment ( 25201988) Hip circumference adjusted for BMI ( 34021172) Intelligence (MTAG) ( 29326435) Multiple sclerosis ( 19525953) Plasma anti-thyroglobulin levels ( 29678681) Platelet count ( 32888494 27863252) Plateletcrit ( 27863252) Schizophrenia ( 28991256 25056061 29483656 30285260 23974872) Tourette syndrome ( 30818990) Type 2 diabetes ( 24509480 30297969 29632382) Type 2 diabetes (adjusted for BMI) ( 29632382) Venous thromboembolism ( 31420334) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Age-related cognitive decline (language) (slope of z-scores) ( 30954325) Bone fracture in osteoporosis ( 28580392) Dilated cardiomyopathy ( 33495596) Dilated cardiomyopathy (MTAG) ( 33495596) Estimated glomerular filtration rate ( 31152163) Lung function (FEV1/FVC) ( 28166213) Metabolite levels ( 23823483) Neurofibrillary tangles ( 25188341) Normalized brain volume ( 19010793) Platelet thrombus formation ( 22550155) Plateletcrit ( 32888494)
Interacting Genes		18 interacting genes: ACACA ALPP ANXA11 ARF5 ATP6V0A2 CABP1 GSK3A HCAR3 KNTC1 MLEC MRPL19 RAB35 SNRNP35 SRSF9 SVIL TRA2A YWHAG YWHAZ	36 interacting genes: AR ATRX BUB1 CENPF DYNLT1 ESR1 FLNA HAX1 HMMR HSP90AA1 ITGB3BP KIF22 KIFC3 KMT2A KRT18 LMNA LMNB2 LUC7L2 MIF4GD MPHOSPH9 MRTFB NME2 NR3C1 ODF2 P2RX7 PAN3 PCNX3 PPARG SH3PXD2A SLAMF7 STARD9 TGFB1I1 TNFAIP1 TRIP6 UXT YWHAG
Entrez ID		10198	6840
HPRD ID		12022	04992
Ensembl ID		ENSG00000051825	ENSG00000197321
Uniprot IDs		Q99550	A0A6I8PIX7 O95425 Q569J5
PDB IDs			2K6M 2K6N
Enriched GO Terms of Interacting Partners?
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