LHFPL2 and TMEM147

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		LHFPL2	TMEM147
Description		LHFPL tetraspan subfamily member 2	transmembrane protein 147
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component Plasma Membrane Membrane Integral Component Of Membrane Platelet Alpha Granule Membrane	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane Protein-containing Complex
	Molecular Function	Molecular_function Protein Binding	Protein Binding Ribosome Binding
	Biological Process	Single Fertilization Biological_process Development Of Primary Female Sexual Characteristics Development Of Primary Male Sexual Characteristics Positive Regulation Of Fertilization
Pathways		Platelet degranulation
Drugs
Diseases
GWAS		Birth weight ( 31043758) Blood and toenail selenium levels ( 25343990) Hippocampal atrophy ( 19668339) Macular thickness ( 30535121) Metabolite levels ( 23823483) Parkinson's disease (familial, age at onset) ( 27402877) Platelet count ( 32888494 27863252) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Pulse pressure ( 28135244 27841878 30578418) Systolic blood pressure ( 27841878 30578418)	Alanine aminotransferase levels ( 33547301) Liver enzyme levels (alanine transaminase) ( 33972514)
Interacting Genes		11 interacting genes: FXYD6 GAST GJA5 GJB1 GPR152 OLFM4 SCARF1 SNORC TBCA TMEM128 TMEM147	55 interacting genes: ABHD16A ABI3 CD200 CD40 CD79A CLDN7 CLN8 CLRN1 CREB3L1 CXCR2 DPM3 EBP EFNA4 ENPP4 F11R FFAR2 GJA8 GLP1R GOLM1 GPR101 GPR37L1 GPR42 GPR61 HTR2C IL3RA KASH5 LDLRAD1 LEUTX LHFPL2 MTIF3 MUC1 PACC1 PDCD1LG2 PSCA PVR RMDN3 RNF185 SCAMP4 SHISA3 SLC10A1 SLC12A7 SLC13A4 SLC22A1 SLC22A2 SUSD3 SYNE4 TACR1 TEX29 TMEM14B TMEM237 TMEM248 TMEM252 TMEM42 TMEM52B TSPAN12
Entrez ID		10184	10430
HPRD ID		17272	17633
Ensembl ID		ENSG00000145685	ENSG00000105677
Uniprot IDs		A0A024RAM8 Q6ZUX7	Q9BVK8
PDB IDs			6W6L
Enriched GO Terms of Interacting Partners?
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