TOB1 and SCMH1

Number of citations of the paper that reports this interaction (PubMedID 16169070)
888

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		TOB1	SCMH1
Description		transducer of ERBB2, 1	Scm polycomb group protein homolog 1
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm CCR4-NOT Complex	Nucleus Nucleoplasm Chromocenter
	Molecular Function	Transcription Corepressor Activity Protein Binding Receptor Tyrosine Kinase Binding SMAD Binding	Chromatin Binding Protein Binding Histone Binding
	Biological Process	Negative Regulation Of Cell Population Proliferation Regulation Of Gene Expression Negative Regulation Of Translation Negative Regulation Of BMP Signaling Pathway Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Regulation Of SMAD Protein Signal Transduction Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay	Chromatin Remodeling Spermatogenesis Anterior/posterior Pattern Specification Gene Silencing Negative Regulation Of Transcription, DNA-templated
Pathways
Drugs			Mercaptoethanol
Diseases
GWAS		Blood protein levels ( 28240269)	Adventurousness ( 30643258) Appendicular lean mass ( 33097823) Atrial fibrillation ( 30061737 29892015) General risk tolerance (MTAG) ( 30643258) Height ( 20881960 25282103 23563607 18391952) Hip circumference adjusted for BMI ( 34021172) Intelligence ( 28530673) Intelligence (MTAG) ( 29326435) Rapid response to perioperative phenylephrine (change in mean arterial pressure) ( 33168928)
Interacting Genes		20 interacting genes: APP CDC7 CNOT7 CORO7 DTL ERBB2 IKZF3 MAPK1 MAPK9 MARCKS PABPC1 SCMH1 SETDB1 SMAD1 SMAD2 SMAD3 SMAD4 SMAD5 SMAD6 SMAD9	22 interacting genes: EWSR1 FXR1 FXR2 GMNN HK1 HPCAL4 LYPLA2 LZTR1 MAGEA12 MAML3 MOB4 PCBD1 PHC1 PHC2 POLR2M SFMBT1 SFMBT2 TMEM11 TOB1 TSC1 UBQLN1 UBQLN4
Entrez ID		10140	22955
HPRD ID		09273	11540
Ensembl ID		ENSG00000141232	ENSG00000010803
Uniprot IDs		P50616	B3KMZ7 Q96GD3
PDB IDs		2D5R 2Z15 5CI8 5CI9	2P0K
Enriched GO Terms of Interacting Partners?
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