LRPPRC and HEBP2

Number of citations of the paper that reports this interaction (PubMedID 11827465)
35

Data Source:
HPRD (two hybrid)

		LRPPRC	HEBP2
Description		leucine rich pentatricopeptide repeat containing	heme binding protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Condensed Nuclear Chromosome Nucleus Nuclear Inner Membrane Nuclear Outer Membrane Nucleoplasm Mitochondrion Cytoskeleton Microtubule Membrane Mitochondrial Nucleoid Perinuclear Region Of Cytoplasm Ribonucleoprotein Complex	Extracellular Region Cytoplasm Mitochondrion Azurophil Granule Lumen Extracellular Exosome
	Molecular Function	Single-stranded DNA Binding RNA Binding Protein Binding Microtubule Binding Ubiquitin Protein Ligase Binding Beta-tubulin Binding Actin Filament Binding	Protein Binding Heme Binding
	Biological Process	Negative Regulation Of Mitochondrial RNA Catabolic Process Mitochondrion Transport Along Microtubule MRNA Transport Regulation Of Mitochondrial Translation	Negative Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Necrotic Cell Death Positive Regulation Of Mitochondrial Membrane Permeability Regulation Of Response To Reactive Oxygen Species
Pathways		TP53 Regulates Metabolic Genes Respiratory electron transport Cytoprotection by HMOX1	Neutrophil degranulation
Drugs
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30679032) Alcohol use disorder (consumption score) ( 33861876) Bitter alcoholic beverage consumption ( 31046077) Chronotype ( 30696823) Frailty index ( 34431594) Hand grip strength ( 29691431 29313844) Levodopa-induced dyskinesia in levodopa treated Parkinson's disease ( 32733355) Medication use (calcium channel blockers) ( 31015401) Medication use (HMG CoA reductase inhibitors) ( 31015401) Morning person ( 30696823) Refractive error ( 32231278) Smoking status (ever vs never smokers) ( 30643258)
Interacting Genes		83 interacting genes: ANKRD1 AP2A2 CECR2 FOXO1 HEBP2 LINC01554 MAP1S MIR1-1 MIR1-2 MIR106A MIR106B MIR107 MIR10B MIR122 MIR128-1 MIR128-2 MIR138-1 MIR138-2 MIR140 MIR141 MIR143 MIR145 MIR155 MIR15A MIR15B MIR16-1 MIR16-2 MIR17 MIR18A MIR18B MIR199A1 MIR199A2 MIR19A MIR19B1 MIR19B2 MIR200A MIR200B MIR200C MIR205 MIR206 MIR20A MIR20B MIR21 MIR214 MIR221 MIR222 MIR25 MIR29A MIR29B1 MIR29B2 MIR29C MIR31 MIR34A MIR34B MIR34C MIR363 MIR429 MIR451A MIR7-1 MIR7-2 MIR7-3 MIR9-1 MIR9-2 MIR9-3 MIR92A1 MIR92A2 MIR93 MIR98 MIRLET7A1 MIRLET7A2 MIRLET7A3 MIRLET7B MIRLET7C MIRLET7D MIRLET7E MIRLET7F1 MIRLET7F2 MIRLET7G MIRLET7I NFKBIB PPARGC1A PTEN UXT	4 interacting genes: LAMTOR5 LRPPRC PDCD6 PLEKHF2
Entrez ID		10128	23593
HPRD ID		06343	09316
Ensembl ID		ENSG00000138095	ENSG00000051620
Uniprot IDs		E5KNY5 P42704	Q5THN1 Q9Y5Z4
PDB IDs			3R85 3R8J 3R8K 4AYZ 4B0Y 5GQQ
Enriched GO Terms of Interacting Partners?
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