HIPK3 and SRSF5

Number of citations of the paper that reports this interaction (PubMedID 16000324)
27

Data Source:
BioGRID (unspecified method)

		HIPK3	SRSF5
Description		homeodomain interacting protein kinase 3	serine and arginine rich splicing factor 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane Nuclear Body PML Body	Nucleoplasm Nucleolus Cytosol Nuclear Speck
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Tyrosine Kinase Activity ATP Binding Protein Serine Kinase Activity	RNA Binding MRNA Binding Protein Binding Protein Kinase B Binding
	Biological Process	Protein Phosphorylation Apoptotic Process MRNA Transcription Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Peptidyl-tyrosine Phosphorylation Negative Regulation Of Apoptotic Process Negative Regulation Of JUN Kinase Activity	MRNA Splicing, Via Spliceosome MRNA Splice Site Selection MRNA Processing Cellular Response To Insulin Stimulus Positive Regulation Of RNA Splicing Regulation Of Cell Cycle Liver Regeneration
Pathways			Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs		Fostamatinib
Diseases
GWAS		Anger ( 24489884) Obese vs. thin ( 30677029) Sleep (1/3-day periodicity) ( 33075057) Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Mean spheric corpuscular volume ( 32888494) Red blood cell count ( 32888494)
Interacting Genes		38 interacting genes: AR ARRB2 C1QA CREB1 CREBBP DAXX FADD FAS FLNC GLUL GORASP1 GRB2 HEYL HNRNPA1 HNRNPA2B1 HNRNPH1 LIMD1 LIMK2 LIMS2 MBD1 MTMR4 NR2F2 RGS3 SIAH1 SIAH2 SKIL SNIP1 SRSF1 SRSF5 SUMO1 TGFB1I1 TOX4 TP73 TRA2B UBE2I WT1 ZNF107 ZYX	20 interacting genes: CALM1 CCR2 CD101 CLK1 DYRK1A HIPK3 MAPK14 MAPK6 OLFM2 PPARGC1A RPS6KA1 SMURF1 SNRPF SREK1 SRPK1 SRPK2 SRSF1 TIAM1 TNK2 ZRSR2
Entrez ID		10114	6430
HPRD ID		05111	02948
Ensembl ID		ENSG00000110422	ENSG00000100650
Uniprot IDs		A8KAE4 Q9H422	A0A024R6D8 Q13243 Q86U32
PDB IDs
Enriched GO Terms of Interacting Partners?
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