DNM1L and SCG3

Number of citations of the paper that reports this interaction (PubMedID 18330356)
6

Data Source:
BioGRID (two hybrid)

		DNM1L	SCG3
Description		dynamin 1 like	secretogranin III
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Cytoplasm Mitochondrion Mitochondrial Outer Membrane Peroxisome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Microtubule Brush Border Clathrin-coated Pit Membrane Synaptic Vesicle Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Presynaptic Endocytic Zone Membrane Mitochondrion-derived Vesicle	Extracellular Region Endoplasmic Reticulum Lumen Transport Vesicle Membrane Secretory Granule Membrane Secretory Granule Lumen
	Molecular Function	GTPase Activity GTPase Activator Activity Protein Binding GTP Binding Microtubule Binding Lipid Binding Clathrin Binding GTP-dependent Protein Binding Small GTPase Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Protein Homodimerization Activity Protein-containing Complex Binding BH2 Domain Binding	RNA Binding Protein Binding
	Biological Process	Mitochondrial Fission Release Of Cytochrome C From Mitochondria Dynamin Family Protein Polymerization Involved In Mitochondrial Fission Calcium Ion Transport Mitochondrion Organization Endoplasmic Reticulum Organization Regulation Of Gene Expression Negative Regulation Of Mitochondrial Fusion Regulation Of Mitochondrion Organization Peroxisome Fission Synaptic Vesicle Recycling Via Endosome Positive Regulation Of Apoptotic Process Mitochondrial Fragmentation Involved In Apoptotic Process Intracellular Distribution Of Mitochondria Synaptic Vesicle Endocytosis Rhythmic Process Positive Regulation Of Protein Secretion Protein Complex Oligomerization Heart Contraction Positive Regulation Of Dendritic Spine Morphogenesis Membrane Fusion Protein-containing Complex Assembly Necroptotic Process Mitochondrion Morphogenesis Protein Localization To Mitochondrion Positive Regulation Of Neutrophil Chemotaxis Positive Regulation Of Mitochondrial Fission Mitochondrial Membrane Fission Positive Regulation Of Release Of Cytochrome C From Mitochondria Cellular Response To Oxygen-glucose Deprivation Regulation Of Peroxisome Organization Positive Regulation Of Synaptic Vesicle Endocytosis Regulation Of Autophagy Of Mitochondrion Regulation Of ATP Metabolic Process Cellular Response To Thapsigargin Regulation Of Ubiquitin Protein Ligase Activity Response To Flavonoid Response To Hypobaric Hypoxia Positive Regulation Of Synaptic Vesicle Exocytosis Positive Regulation Of Intrinsic Apoptotic Signaling Pathway	Protein Localization To Secretory Granule
Pathways		Apoptotic execution phase	Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation
Drugs
Diseases
GWAS		Mean platelet volume ( 32888494) Platelet count ( 32888494) Platelet distribution width ( 32888494)	Asthma ( 20159242) Blood protein levels ( 30072576 29875488) Intelligence (MTAG) ( 29326435) Mean reticulocyte volume ( 32888494)
Interacting Genes		20 interacting genes: FIS1 FZR1 GSK3B MAGEA1 MAGEA3 MAP3K10 MFF MIEF1 MIEF2 MUL1 PINK1 PRKN RRM2 SCG3 SENP3 SH3GL1 SIRT3 SUMO2 VIM ZBTB24	4 interacting genes: CHGA DNM1L SDCBP TCF12
Entrez ID		10059	29106
HPRD ID		04833	11538
Ensembl ID		ENSG00000087470	ENSG00000104112
Uniprot IDs		B4DYR6 O00429	Q8WXD2
PDB IDs		3W6N 3W6O 3W6P 4BEJ 4H1U 4H1V 5WP9
Enriched GO Terms of Interacting Partners?
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