ISY1-RAB43 and FARS2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
86

Data Source:
BioGRID (two hybrid)

		ISY1-RAB43	FARS2
Description		ISY1-RAB43 readthrough	phenylalanyl-tRNA synthetase 2, mitochondrial
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GO Annotations	Cellular Component		Cytoplasm Mitochondrion Mitochondrial Matrix
	Molecular Function		TRNA Binding Phenylalanine-tRNA Ligase Activity Protein Binding ATP Binding
	Biological Process		TRNA Aminoacylation For Protein Translation Phenylalanyl-tRNA Aminoacylation TRNA Processing
Pathways		Formation of TC-NER Pre-Incision Complex Transcription-Coupled Nucleotide Excision Repair (TC-NER) Dual incision in TC-NER Gap-filling DNA repair synthesis and ligation in TC-NER mRNA Splicing - Major Pathway	Mitochondrial tRNA aminoacylation
Drugs			Phenylalanine
Diseases
GWAS		Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971)	Change in glucose in response to thiazide diuretic treatment in hypertension ( 29523524) Copper levels ( 26025379) Height ( 28552196) JT interval (sulfonylurea treatment interaction) ( 27958378) Metabolite levels ( 23823483) Obesity (early onset extreme) ( 23563609) Subjective response to placebo treatment in childhood asthma (change in cough/wheeze) ( 31557306)
Interacting Genes		14 interacting genes: CCDC185 EXOC8 FAM161B FARS2 FBXO44 FRS3 LENG1 NME7 NXF1 RCOR3 TSTD2 UBASH3A ZNF587 ZNF629	69 interacting genes: ADAMTSL4 AGTRAP AJUBA AP1B1 APPL1 BACH2 BAG4 BANP BEX5 CALCOCO2 CBY2 CCDC152 CDCA4 CMTM5 CYSRT1 DGAT2L6 DPH2 DVL3 FHL5 FKBP7 FSD2 GRB10 HIGD1C HMBOX1 HOMEZ IKZF3 ISY1-RAB43 KCNF1 KCTD17 KRT13 KRT31 KRT34 KRT40 KRTAP1-1 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP3-3 MAN1C1 MDFI MESD MID2 MKRN3 MORN3 NFKBID NOTCH2NLA PCSK5 PPP1R16B RCBTB2 RIMBP3C SPRY1 STX11 SYP TADA2A TEPSIN TFCP2 TPM2 TRAF2 TRIM27 TRIM54 TRIP6 YIF1A ZNF438 ZNF500 ZNF526 ZNF655 ZRANB1
Entrez ID		100534599	10667
HPRD ID			09946
Ensembl ID		ENSG00000261796	ENSG00000145982
Uniprot IDs		Q9ULR0	O95363
PDB IDs		5YZG 6FF7 6ZYM 7A5P	3CMQ 3HFV 3TEG 3TUP 5MGH 5MGU 5MGV 5MGW
Enriched GO Terms of Interacting Partners?
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