S1PR2

Description		sphingosine-1-phosphate receptor 2
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Membrane
	Molecular Function	G Protein-coupled Receptor Binding G Protein-coupled Receptor Activity Integrin Binding Protein Binding Lipid Binding G Protein-coupled Peptide Receptor Activity Sphingosine-1-phosphate Receptor Activity
	Biological Process	Sphingosine-1-phosphate Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Population Proliferation Positive Regulation Of Peptidyl-threonine Phosphorylation Negative Regulation Of Smooth Muscle Cell Migration Regulation Of Metabolic Process Actin Cytoskeleton Reorganization Filopodium Assembly Negative Regulation Of Excitatory Postsynaptic Potential Positive Regulation Of Establishment Of Endothelial Barrier Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Pathways		G alpha (i) signalling events Lysosphingolipid and LPA receptors
Drugs
Diseases
GWAS		Alanine aminotransferase levels ( 33547301 33339817) Alanine transaminase levels ( 29403010) High light scatter reticulocyte count ( 32888494 27863252) High light scatter reticulocyte percentage of red cells ( 32888494 27863252) Immature fraction of reticulocytes ( 32888494 27863252) Liver enzyme levels (alanine transaminase) ( 33972514) Liver enzyme levels (alkaline phosphatase) ( 33972514) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Reticulocyte count ( 32888494 27863252) Reticulocyte fraction of red cells ( 32888494 27863252) Serum alkaline phosphatase levels ( 33547301) Systolic blood pressure ( 30578418) White blood cell count ( 32888494)
Interacting Genes		4 interacting genes: GNA13 GNAI1 GNAQ KEAP1
Entrez ID		9294
HPRD ID		05488
Ensembl ID		ENSG00000267534
Uniprot IDs		A0A024R7B2 O95136
PDB IDs		1ZTI
Enriched GO Terms of Interacting Partners?
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