METAP1

Description		methionyl aminopeptidase 1
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GO Annotations	Cellular Component	Cytoplasm Cytosol
	Molecular Function	Aminopeptidase Activity Protein Binding Metalloexopeptidase Activity Metal Ion Binding Metalloaminopeptidase Activity
	Biological Process	Regulation Of Translation Proteolysis Peptidyl-methionine Modification N-terminal Protein Amino Acid Modification Protein Initiator Methionine Removal Platelet Aggregation
Pathways		Inactivation, recovery and regulation of the phototransduction cascade
Drugs		Ovalicin 5-CHLORO-6-METHYL-N-(2-PHENYLETHYL)-2-PYRIDIN-2-YLPYRIMIDIN-4-AMINE TERT-BUTYL {2-[(1,3-THIAZOL-2-YLAMINO)CARBONYL]PYRIDIN-3-YL}CARBAMATE 3-[(2,2-DIMETHYLPROPANOYL)AMINO]-N-1,3-THIAZOL-2-YLPYRIDINE-2-CARBOXAMIDE
Diseases
GWAS		Alcohol consumption (drinks per week) ( 30643258) Alcohol dependence ( 33290381) Alcohol use disorder (consumption score) ( 30336701) Alcohol use disorder (dependence and problematic use scores) ( 30336701) Alcohol use disorder (total score) ( 30336701) Oral cavity and pharyngeal cancer ( 27749845) Regular attendance at a pub or social club ( 29970889)
Interacting Genes		7 interacting genes: GLRX3 INCA1 MEOX2 NBR1 PLEKHG4 SMAD9 ZRANB1
Entrez ID		23173
HPRD ID		10071
Ensembl ID		ENSG00000164024
Uniprot IDs		P53582
PDB IDs		2B3H 2B3K 2B3L 2G6P 2GZ5 2NQ6 2NQ7 4FLI 4FLJ 4FLK 4FLL 4HXX 4IKR 4IKS 4IKT 4IKU 4IU6 4U1B 4U69 4U6C 4U6E 4U6J 4U6W 4U6Z 4U70 4U71 4U73 4U75 4U76 5YKP 5YR4 5YR5 5YR6 5YR7 6LZB 6LZC
Enriched GO Terms of Interacting Partners?
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