NLRP1

Description		NLR family pyrin domain containing 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Inflammasome Complex NLRP1 Inflammasome Complex
	Molecular Function	Double-stranded DNA Binding Double-stranded RNA Binding Protein Binding ATP Binding Peptidase Activity Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process ATP Hydrolysis Activity Enzyme Binding Protein Domain Specific Binding Protein Self-association Cysteine-type Endopeptidase Activator Activity
	Biological Process	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Inflammatory Response Response To Muramyl Dipeptide Positive Regulation Of Interleukin-1 Beta Production Defense Response To Bacterium Regulation Of Apoptotic Process Regulation Of Inflammatory Response Protein Homooligomerization Neuron Apoptotic Process Defense Response To Virus Pyroptosis Self Proteolysis Antiviral Innate Immune Response NLRP1 Inflammasome Complex Assembly
Pathways		The NLRP1 inflammasome
Drugs
Diseases
GWAS		Migraine ( 27322543)
Interacting Genes		9 interacting genes: APAF1 BCL2 BCL2L1 CASP1 CASP2 CASP5 CASP9 NOD1 PYCARD
Entrez ID		22861
HPRD ID		07364
Ensembl ID		ENSG00000091592
Uniprot IDs		Q9C000
PDB IDs		1PN5 3KAT 4IFP 4IM6 5Y3S 6K7V 6XKK
Enriched GO Terms of Interacting Partners?
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