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DUSP9

Description dual specificity phosphatase 9
Image
GO Annotations Cellular Component
  • Nucleus
  • Cytoplasm
  • Cytosol
Molecular Function
  • Phosphoprotein Phosphatase Activity
  • Protein Tyrosine Phosphatase Activity
  • Protein Binding
  • Protein Tyrosine/serine/threonine Phosphatase Activity
  • Protein Tyrosine/threonine Phosphatase Activity
  • MAP Kinase Tyrosine/serine/threonine Phosphatase Activity
  • Protein Serine Phosphatase Activity
  • Protein Threonine Phosphatase Activity
Biological Process
  • MAPK Cascade
  • JNK Cascade
  • Positive Regulation Of Apoptotic Process
  • Negative Regulation Of MAPK Cascade
  • Regulation Of Heart Growth
  • Negative Regulation Of ERK1 And ERK2 Cascade
Pathways
  • RAF-independent MAPK1/3 activation
  • Negative regulation of MAPK pathway
  • Signaling by MAPK mutants
Drugs
Diseases
GWAS
  • Body mass index ( 28892062)
  • Creatinine levels ( 29403010)
  • Estimated glomerular filtration rate ( 31015462)
  • Glomerular filtration rate ( 29403010)
  • Hemoglobin A1c levels ( 29403010)
  • Type 2 diabetes ( 23945395 22961080 20581827 30718926)
Interacting Genes 7 interacting genes: AATK CDK4 GSK3B MAPK1 MAPK10 MAPK14 MAPK3
Entrez ID 1852
HPRD ID 02136
Ensembl ID ENSG00000130829
Uniprot IDs B2RAL9 Q6P9C2 Q99956
PDB IDs 2HXP 3LJ8
Enriched GO Terms of Interacting Partners?
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© Madhavi K. Ganapathiraju 2012-2025