CENPE

Description		centromere protein E
Image
GO Annotations	Cellular Component	Chromosome, Centromeric Region Kinetochore Condensed Chromosome, Centromeric Region Nucleus Nucleoplasm Chromosome Kinetochore Microtubule Cytosol Microtubule Microtubule Cytoskeleton Membrane Midbody Spindle Midzone Mitotic Spindle Midzone
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding Plus-end-directed Microtubule Motor Activity Kinetochore Binding
	Biological Process	Mitotic Cell Cycle Microtubule-based Movement Mitotic Spindle Organization Chromosome Segregation Mitotic Chromosome Movement Towards Spindle Pole Mitotic Metaphase Plate Congression Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Protein Kinase Activity Cell Division Metaphase Plate Congression Attachment Of Mitotic Spindle Microtubules To Kinetochore Kinetochore Assembly Microtubule Plus-end Directed Mitotic Chromosome Migration Lateral Attachment Of Mitotic Spindle Microtubules To Kinetochore
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins COPI-dependent Golgi-to-ER retrograde traffic Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation Kinesins
Drugs		GSK-923295
Diseases
GWAS		Anti-chlamydia trachomatis IgG seropositivity ( 29967566) Apolipoprotein A1 levels ( 32203549) HDL cholesterol levels ( 32203549) Schizophrenia ( 28991256) Spontaneous preterm birth without premature rupture of membranes ( 31194736) Testicular germ cell tumor ( 25877299 28604728 28604732 23666240)
Interacting Genes		13 interacting genes: BUB1B CENPF CLK1 CUL1 DNAJB1 DUX1 FANCA NUF2 RHEB SEPTIN7 SKP1 TRAF4 UBC
Entrez ID		1062
HPRD ID		00316
Ensembl ID		ENSG00000138778
Uniprot IDs		Q02224
PDB IDs		1T5C 5JVP
Enriched GO Terms of Interacting Partners?
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