G3BP1

Description		G3BP stress granule assembly factor 1
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Focal Adhesion Cytoplasmic Stress Granule Perikaryon Ribonucleoprotein Complex
	Molecular Function	DNA Binding DNA Helicase Activity RNA Binding RNA Helicase Activity MRNA Binding Endonuclease Activity Protein Binding ATP Binding ATP Hydrolysis Activity DNA/RNA Helicase Activity
	Biological Process	Ras Protein Signal Transduction Positive Regulation Of Type I Interferon Production DNA Duplex Unwinding Stress Granule Assembly Innate Immune Response Defense Response To Virus Positive Regulation Of Stress Granule Assembly Negative Regulation Of Canonical Wnt Signaling Pathway Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways
Drugs
Diseases
GWAS		Periventricular white matter hyperintensities ( 32517579) Platelet distribution width ( 32888494) Red cell distribution width ( 32888494)
Interacting Genes		17 interacting genes: APP CSK DNAH1 DTX1 EPHA8 FBXO25 HAND1 HMGXB3 IL7R LCK LINC01554 OGT PIN1 PPIA RASA1 SYNPO USP10
Entrez ID		10146
HPRD ID		06569
Ensembl ID		ENSG00000145907
Uniprot IDs		Q13283 Q5U0Q1 Q6ZP53
PDB IDs		3Q90 4FCJ 4FCM 4IIA 5FW5
Enriched GO Terms of Interacting Partners?
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