MVP and CKAP4

Data Source:
BioGRID (two hybrid)

		MVP	CKAP4
Description		major vault protein	cytoskeleton associated protein 4
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Nucleus Nuclear Pore Cytoplasm Cytosol Cytoskeleton Membrane Secretory Granule Lumen Perinuclear Region Of Cytoplasm Extracellular Exosome Ficolin-1-rich Granule Lumen	Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Lipid Droplet Cytosol Cytoskeleton Plasma Membrane Membrane Integral Component Of Membrane Nuclear Speck Azurophil Granule Membrane Specific Granule Membrane Cytoplasmic Ribonucleoprotein Granule Lamellar Body Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function	Protein Binding Protein Kinase Binding Protein Phosphatase Binding Identical Protein Binding	RNA Binding
	Biological Process	Protein Transport Negative Regulation Of Protein Autophosphorylation ERBB Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Neutrophil Degranulation MRNA Transport Negative Regulation Of Protein Tyrosine Kinase Activity	Neutrophil Degranulation Post-translational Protein Modification Cellular Protein Metabolic Process
Pathways		Neutrophil degranulation	Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Surfactant metabolism Neutrophil degranulation Post-translational protein phosphorylation
Drugs
Diseases
GWAS			Basophil count ( 32888494) Basophil percentage of white cells ( 32888494) Metabolite levels ( 23823483) Refractive error ( 32231278)
Interacting Genes		64 interacting genes: ADAMTSL4 BANP C1orf94 CALCOCO2 CAMK2B CKAP4 DISC1 DLX2 DTX2 EPHX2 ESR1 FNDC3B GIT2 GOLGA2 HP IHO1 KCTD9 KPNA2 KPNA3 MDFI MEOX1 MEOX2 MID2 MRTFA MT-CYB NNT NOTCH2NLA NRF1 NTAQ1 PARP4 PIH1D2 PLSCR1 POT1 PSTPIP1 PTEN PTPN11 RAB3IP RBPMS REL RHOXF2 RIMBP3 RNF111 SAXO1 SERTAD1 SKIL SLC2A4 STN1 TCF4 TENT5C TFCP2 TLE5 TOLLIP TP53 TRAF2 TRIM27 TRIM42 TRIP13 TRIP6 TSPOAP1 UBC UBTD2 VAC14 ZBTB32 ZMIZ2	13 interacting genes: ASCC2 ATF4 DKK1 HAMP LINC01554 MLH1 MVP NDUFB7 NKX3-1 PLAT THOC7 TSNAX WASHC3
Entrez ID		9961	10970
HPRD ID		05475	16717
Ensembl ID		ENSG00000013364	ENSG00000136026
Uniprot IDs		Q14764 X5D2M8 X5D7K9 X5DNU0	A0A024RBH2 Q07065
PDB IDs		1Y7X
Enriched GO Terms of Interacting Partners?
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