EPM2AIP1 and KRT16

Data Source:
BioGRID (two hybrid)

		EPM2AIP1	KRT16
Description		EPM2A interacting protein 1	keratin 16
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasmic Side Of Endoplasmic Reticulum Membrane	Nucleus Cytosol Cytoskeleton Intermediate Filament Extracellular Exosome
	Molecular Function	Protein Binding Identical Protein Binding	Structural Constituent Of Cytoskeleton Protein Binding
	Biological Process	Response To Insulin Positive Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Glycogen (starch) Synthase Activity	Morphogenesis Of An Epithelium Inflammatory Response Cytoskeleton Organization Aging Keratinocyte Differentiation Negative Regulation Of Cell Migration Keratinization Hair Cycle Innate Immune Response Intermediate Filament Cytoskeleton Organization Keratinocyte Migration Establishment Of Skin Barrier Cornification
Pathways			Keratinization Formation of the cornified envelope
Drugs			Zinc Zinc acetate
Diseases			Non-epidermolytic palmoplantar keratoderma (NEPPK) Pachyonychia congenita, including: Jadassohn-Lewandowsky syndrome; Jackson-Lawler syndrome ; Steatocystoma multiplex
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Subjective response to lithium treatment ( 26503763) Triglyceride levels ( 32203549)
Interacting Genes		46 interacting genes: ACTN1 APPL2 ARHGEF5 C1orf50 CBFA2T3 CCNB1IP1 CNTROB CPSF7 DTX3 EMP2 EPM2A FHL3 GFAP HSF2BP KCTD1 KCTD9 KRT16 KRT75 LDB2 LIN52 LNX1 MAD2L1 MEOX2 MX1 NOC4L OTUD7B PICK1 PRTFDC1 PSMA7 RBMY1F RBMY1J REL SERPINF1 SWSAP1 TFIP11 TNFAIP1 TNKS TRA2B TRIM50 TRIM54 USP54 VPS52 ZBTB14 ZIM2 ZNF620 ZSCAN18	56 interacting genes: AMOT ARFIP2 C1orf109 C1orf216 CARD9 CCDC146 CCDC17 CCHCR1 CCNC CDK18 CYTH4 EPM2AIP1 GAS8 GNG10 HGS KIFC3 KLC4 KRT1 KRT2 KRT3 KRT4 KRT5 KRT6A KRT6C KRT71 KRT72 KRT73 KRT74 KRT76 KRT78 KRT79 KRT8 KRT80 KRT81 KRT83 KRT85 KRT86 LMO1 LNX1 MBD3 PKN1 POLL PPP1R18 PRKAA2 PRPH PUS10 SEMA4C SGF29 SMARCD1 SMARCE1 SNAPIN TCHP TSG101 TTC23 TXLNB USHBP1
Entrez ID		9852	3868
HPRD ID		07445	01018
Ensembl ID		ENSG00000178567	ENSG00000186832
Uniprot IDs		Q7L775	P08779
PDB IDs
Enriched GO Terms of Interacting Partners?
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