SEC22B and GJB6

Data Source:
BioGRID (two hybrid)

		SEC22B	GJB6
Description		SEC22 homolog B, vesicle trafficking protein	gap junction protein beta 6
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Synaptic Vesicle ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane Transport Vesicle COPI-coated Vesicle Phagocytic Vesicle Membrane SNARE Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome	Cytosol Actin Filament Gap Junction Connexin Complex Integral Component Of Membrane Apical Plasma Membrane Cell Junction
	Molecular Function	SNAP Receptor Activity Protein Binding Syntaxin Binding	Gap Junction Channel Activity Protein Binding Microtubule Binding Beta-tubulin Binding Actin Filament Binding Gap Junction Channel Activity Involved In Cell Communication By Electrical Coupling
	Biological Process	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Transport Positive Regulation Of Protein Catabolic Process COPII Vesicle Coating Vesicle Fusion With Golgi Apparatus Negative Regulation Of Autophagosome Assembly Vesicle Fusion With Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Membrane	Apoptotic Process Cell-cell Signaling Aging Sensory Perception Of Sound Negative Regulation Of Cell Population Proliferation Cell Communication By Electrical Coupling Gap Junction Assembly Response To Lipopolysaccharide Maintenance Of Blood-brain Barrier Ear Morphogenesis Inner Ear Development Response To Electrical Stimulus Transmembrane Transport Cellular Response To Glucose Stimulus Gap Junction-mediated Intercellular Transport
Pathways		ER-Phagosome pathway COPII-mediated vesicle transport Cargo concentration in the ER COPI-dependent Golgi-to-ER retrograde traffic	Gap junction assembly
Drugs
Diseases			Ectodermal dysplasia, hidrotic; Clouston syndrome Deafness, autosomal recessive
GWAS		Iris color (L* coordinate) ( 30895295)	Facial emotion recognition (happy faces) ( 28608620)
Interacting Genes		56 interacting genes: ABHD16A AIG1 AQP6 B3GAT3 CD79A CERS6 CLDN7 CLRN1 CPLX4 CREB3 CREB3L1 DPM3 EBP ELOVL4 ERGIC3 FAM174A FAM209A FCER1G FNDC9 GJA8 GJB5 GJB6 GORAB GPR152 GPX8 HIBADH HSD17B11 HSD17B13 IFNGR2 JAGN1 KIR2DL3 LHFPL1 LHFPL5 LMNA MFF MFSD5 MGST2 MGST3 MMGT1 MRPS18B NDUFAF2 REEP4 RELL2 RHBDD1 SERINC2 SLC35C2 STX1A STX2 STX4 STX5 TLCD4 TM4SF19 TMEM139 TMEM167B TMEM229B TMEM86B	14 interacting genes: CHRM5 CNST EBP F2RL1 GJB2 GPR61 KLRC1 LHFPL5 MS4A13 SEC22A SEC22B SLC10A6 TMEM218 TMEM60
Entrez ID		9554	10804
HPRD ID		04939	05107
Ensembl ID		ENSG00000265808	ENSG00000121742
Uniprot IDs		O75396	A0A024RDS4 O95452
PDB IDs		2NUP 2NUT 3EGD 3EGX
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?