MRRF and ZNF408

Data Source:
BioGRID (two hybrid)

		MRRF	ZNF408
Description		mitochondrial ribosome recycling factor	zinc finger protein 408
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Nucleus
	Molecular Function	Protein Binding Ribosomal Large Subunit Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Translation Ribosome Disassembly Mitochondrial Translational Termination	Regulation Of Transcription By RNA Polymerase II
Pathways		Mitochondrial translation termination
Drugs
Diseases
GWAS			Alzheimer's disease or fasting glucose levels (pleiotropy) ( 30805717) Autism spectrum disorder or schizophrenia ( 28540026) Femoral neck bone mineral density ( 29499414) Schizophrenia ( 29483656)
Interacting Genes		10 interacting genes: AGTRAP APP BANP CMTM5 FAM9B FHL3 KRT40 SYP WIPI2 ZNF408	83 interacting genes: AEBP2 AEN APOBEC3C ATRN BAHD1 CALCOCO2 CCDC136 CEP70 CHAF1A CRELD1 CYSRT1 DDX56 DVL3 EXOSC2 FBLN2 FHL2 FHL5 FSD2 GIPC1 GPATCH2L HNRNPK HOXA5 HOXB9 ID3 KCTD9 KHDRBS3 KRT40 KRTAP1-1 KRTAP10-7 KRTAP10-8 KRTAP12-2 KRTAP12-3 KRTAP4-12 KRTAP5-9 LDOC1 LSM2 LZTS2 MDFI MID2 MIF MRRF MTUS2 NBPF19 NOTCH2NLA PDE4DIP PDLIM4 PICK1 PNMA2 PRAME PRNP PRPF31 PSTPIP1 RALY RALYL RBM10 RBMY1F RBMY1J SAP30BP SPRED1 SSX2IP THAP1 TLE5 TOP3B TRIM23 TRIM41 UBE2I UPF2 USP20 ZBTB26 ZBTB48 ZBTB8A ZBTB9 ZC4H2 ZNF212 ZNF317 ZNF330 ZNF331 ZNF473 ZNF526 ZNF764 ZNF792 ZNF837 ZRANB1
Entrez ID		92399	79797
HPRD ID		06856	18338
Ensembl ID		ENSG00000148187	ENSG00000175213
Uniprot IDs		Q96E11	B4DXY4 Q9H9D4
PDB IDs		6NU2 6ZS9
Enriched GO Terms of Interacting Partners?
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