EBAG9 and CLN6

Data Source:
BioGRID (two hybrid)

		EBAG9	CLN6
Description		estrogen receptor binding site associated antigen 9	CLN6 transmembrane ER protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Integral Component Of Membrane Secretory Granule	Nucleolus Early Endosome Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane Intracellular Membrane-bounded Organelle Membrane Raft
	Molecular Function	Protein Binding Peptidase Activator Activity Involved In Apoptotic Process	Protein Binding Lysophosphatidic Acid Binding Protein Homodimerization Activity Sulfatide Binding
	Biological Process	Regulation Of Cell Growth Apoptotic Process	Ganglioside Metabolic Process Lysosome Organization Lysosomal Lumen Acidification Visual Perception Cholesterol Metabolic Process Protein Catabolic Process Glycosaminoglycan Metabolic Process Locomotion Involved In Locomotory Behavior Cellular Macromolecule Catabolic Process Positive Regulation Of Proteolysis
Pathways		Estrogen-dependent gene expression
Drugs
Diseases			Neuronal ceroid lipofuscinosis, including: Infantile Neuronal Ceroid Lipofuscinosis (INCL)/ Santavuori-Haltia Disease (CLN1); Late-Infantile Neuronal Ceroid Lipofuscinosis (LINCL)/ Jansky-Bielschowsky Disease (CLN2); Juvenile Neuronal Ceroid Lipofuscinosis (JNCL)/Batten Disease/ Spielmeyer-Vogt Disease (CLN3); Adult Neuronal Ceroid Lipofuscinosis (ANCL)/ Kufs Disease (CLN4); LINCL variant (CLN5, CLN6, CLN7, CLN8); Batten Disease variant (CLN9); Congenital NCL (CLN10) Progressive myoclonic epilepsy (PME), including: Lafora disease (LBD); Unverricht-Lundborg disease (ULD); Neuronal ceroid lipofuscinoses (NCL); Type I sialidosis; Action myoclonus-renal failure syndrome (AMRF); Type III Gaucher disease (GD)
GWAS		Metabolite levels ( 23823483) Nicotine dependence and major depression (severity of comorbidity) ( 30287806)	Major depressive disorder ( 23377640) Restless legs syndrome ( 29029846)
Interacting Genes		28 interacting genes: ACSL5 APOL2 BNIP3 C14orf180 CFHR5 CIAO2A CLEC4G CLN6 MGLL NEDD4 OR10AG1 ORMDL1 PEX16 PRAF2 REEP6 SLC30A2 SLC35A1 SLC35A4 SLC35B4 SNAPIN STX1A STX2 STX3 TMEM107 TPRG1 TRAF3IP3 VAPA VAPB	26 interacting genes: ARL13B CD79A CISD2 CLDN7 CLEC10A CPLX4 CREB3L1 CYBC1 EBAG9 EVI2B FAM209A FNDC9 GJA8 GORAB KIR2DL3 LIME1 LMNA LRRC25 RIC3 SLC22A23 SLC30A4 STX1A TEX264 TMEM139 TMEM237 TMPRSS2
Entrez ID		9166	54982
HPRD ID		05775	05991
Ensembl ID		ENSG00000147654	ENSG00000128973
Uniprot IDs		A0A024R9E0 O00559	A0A024R601 Q9NWW5
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?