RABEP1 and TNS4

Data Source:
BioGRID (two hybrid)

		RABEP1	TNS4
Description		rabaptin, RAB GTPase binding effector protein 1	tensin 4
Image			No pdb structure
GO Annotations	Cellular Component	Endosome Early Endosome Endocytic Vesicle Early Endosome Membrane Protein-containing Complex Intracellular Membrane-bounded Organelle Recycling Endosome	Cytosol Cytoskeleton Focal Adhesion
	Molecular Function	GTPase Activator Activity Protein Binding Growth Factor Activity Protein Domain Specific Binding Protein Homodimerization Activity	Actin Binding Protein Binding
	Biological Process	Golgi To Plasma Membrane Transport Endocytosis Apoptotic Process Signal Transduction Protein Transport Vesicle-mediated Transport Positive Regulation Of GTPase Activity Membrane Fusion Protein Localization To Ciliary Membrane	Apoptotic Process Protein Localization
Pathways		TBC/RABGAPs	MET interacts with TNS proteins
Drugs
Diseases
GWAS		Body mass index ( 28892062 25673413) Lymphocyte counts ( 32888494) Mean platelet volume ( 32888494) Monocyte count ( 32888494) Red blood cell density in sickle cell anemia ( 28552477) White blood cell count ( 27863252)	Asthma ( 31959851) Pancreatic cancer ( 29422604) Pancreatic ductal adenocarcinoma ( 30541042)
Interacting Genes		58 interacting genes: ABI2 AIMP2 AP1G1 AP1G2 ATXN7 BARD1 CASP3 CCDC120 CCND1 CDC73 CDK18 CDKL3 CEP57 CFAP53 ELOA ESCO2 FAM50B FAM90A1 GAP43 GGA1 GGA2 GGA3 HUNK ITSN1 LENG1 MAT2B MCRS1 ODAD3 PELI2 PKP2 PRPF3 RAB1A RAB33B RAB4A RAB4B RAB5A RABGEF1 RGS17 RNF39 SMURF1 SNAPIN SNW1 SRPK2 STAR TNS4 TRAPPC2L TRIM26 TSC2 TSHZ2 UBC UBTFL1 USP2 UTP14C WASHC3 YWHAG ZNF438 ZNF512B ZNF774	25 interacting genes: AR CARD9 CBL CYSRT1 EGFR ERBB3 ERBB4 GAB1 GSTCD HSF2BP KAZN KCTD4 MET NME4 NR3C1 P4HA2 PIH1D1 PIK3R1 PPP3CA RABEP1 RPAIN TRIM21 TRIM27 TXK ZRANB1
Entrez ID		9135	84951
HPRD ID		04684	12223
Ensembl ID		ENSG00000029725	ENSG00000131746
Uniprot IDs		B4DMM4 Q15276	Q6PJP3 Q8IZW8
PDB IDs		1P4U 1TU3 1X79 4N3Y 4N3Z 4Q9U
Enriched GO Terms of Interacting Partners?
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