ZNF414 and KRT86

Data Source:
BioGRID (two hybrid)

		ZNF414	KRT86
Description		zinc finger protein 414	keratin 86
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Extracellular Space Cytosol Keratin Filament
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Metal Ion Binding	Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Keratinization Cornification
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases			Monilethrix
GWAS			Blond vs. brown/black hair color ( 30531825) Diffusing capacity of carbon monoxide ( 30694715) Diisocyanate-induced asthma ( 25918132) Plasma amyloid beta peptide concentrations (ABx-42) ( 24535457)
Interacting Genes		54 interacting genes: ADAMTSL4 CALCOCO2 CARD10 CFP CNFN CYSRT1 FBLN2 GOLGA2 GOLGA6L9 HOMER3 ITIH6 KANK2 KRT31 KRT34 KRT36 KRT86 KRTAP1-3 KRTAP10-7 KRTAP10-8 KRTAP13-3 KRTAP19-1 KRTAP19-5 KRTAP19-6 KRTAP3-1 KRTAP4-12 KRTAP5-9 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP9-3 MDFI MGAT5B MKRN3 MTUS2 NBPF19 NOTCH2NLA PDE4DIP PICK1 POU2AF1 PPP1R16A RBCK1 RBM11 RNF125 SH2B2 SORBS3 SPRED2 TERF2IP TEX11 TLE5 TRIM10 TRIM27 TRIM42 WWOX ZMYND12	45 interacting genes: CAMK2B CCDC146 CDK18 CEP57 CREB5 CYSRT1 GNE HGS HSD3B7 IL16 JOSD1 KANK2 KRT14 KRT15 KRT16 KRT19 KRT25 KRT27 KRT28 KRT31 KRT32 KRT33B KRT34 KRT35 KRT36 KRT37 KRT38 KRT39 KRT40 KRT76 MAPKBP1 MEOX2 MGAT5B MKRN3 NUTF2 ODF1 OIP5 OLIG3 RESF1 RTP5 SHC3 TEKT4 TSGA10IP ZNF414 ZNF655
Entrez ID		84330	3892
HPRD ID		17511	03567
Ensembl ID		ENSG00000133250	ENSG00000170442
Uniprot IDs		Q96IQ9	A8K872 O43790
PDB IDs
Enriched GO Terms of Interacting Partners?
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