MIEN1 and RNF126

Data Source:
BioGRID (two hybrid)

		MIEN1	RNF126
Description		migration and invasion enhancer 1	ring finger protein 126
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GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Intrinsic Component Of The Cytoplasmic Side Of The Plasma Membrane Centriolar Satellite	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Protein Binding	Epidermal Growth Factor Receptor Binding Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Apoptotic Process Response To Selenium Ion Positive Regulation Of Cell Migration Negative Regulation Of Apoptotic Process Positive Regulation Of Filopodium Assembly	Ubiquitin-dependent Protein Catabolic Process Protein Monoubiquitination Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Cell Population Proliferation Retrograde Transport, Endosome To Golgi Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Cytoplasm Protein Quality Control By The Ubiquitin-proteasome System
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Asthma ( 31619474 29273806) Asthma or allergic disease (pleiotropy) ( 29785011) Systemic lupus erythematosus ( 28714469)	Arterial stiffness ( 31070453) Arterial stiffness index ( 31235810) Pulse pressure ( 30578418)
Interacting Genes		14 interacting genes: ARID5A DDIT4L GORASP2 HDAC7 HIVEP1 HLX HMGB2 NLGN3 POU6F2 REL RNF126 TRIP6 VENTX ZBTB32	39 interacting genes: AICDA BAG6 CDKN1A CENPP CSNK2B E2F1 EGFR FXN HMGCL MAP3K1 MDM2 MIEN1 NUDT3 OTUB1 OTUB2 PLK1 PSMF1 RBX1 RNF168 SNUPN TRIM11 TRIM23 TRIM26 TRIM52 TSG101 UBC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E2 UBE2E3 UBE2N UBL3 UBL4A USP15 USP2 XRCC5 XRCC6
Entrez ID		84299	55658
HPRD ID		12681	11501
Ensembl ID		ENSG00000141741	ENSG00000070423
Uniprot IDs		J3KTI2 Q9BRT3	A0A024R206 A8K0Q1 Q9BV68
PDB IDs		2LJK	2N9O 2N9P
Enriched GO Terms of Interacting Partners?
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