TUBB2A and SERPINB9

Data Source:
BioGRID (two hybrid)

		TUBB2A	SERPINB9
Description		tubulin beta 2A class IIa	serpin family B member 9
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Extracellular Exosome Extracellular Vesicle	Extracellular Space Nucleus Nucleoplasm Cytoplasm Golgi Apparatus Cytosol Membrane Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	GTPase Activity Structural Constituent Of Cytoskeleton Protein Binding GTP Binding	Protease Binding Serine-type Endopeptidase Inhibitor Activity Protein Binding Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Neuron Migration	Mast Cell Mediated Immunity Apoptotic Process Immune Response Response To Bacterium Positive Regulation Of Gene Expression Negative Regulation Of Endopeptidase Activity Negative Regulation By Symbiont Of Host Apoptotic Process Protection From Natural Killer Cell Mediated Cytotoxicity Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cellular Response To Estrogen Stimulus
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane Gap junction assembly MHC class II antigen presentation Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion HSP90 chaperone cycle for steroid hormone receptors (SHR) Recruitment of NuMA to mitotic centrosomes Prefoldin mediated transfer of substrate to CCT/TriC Formation of tubulin folding intermediates by CCT/TriC Post-chaperonin tubulin folding pathway Recycling pathway of L1 Recycling pathway of L1 Hedgehog 'off' state Cilium Assembly Intraflagellar transport RHO GTPases activate IQGAPs RHO GTPases Activate Formins COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic COPI-independent Golgi-to-ER retrograde traffic Mitotic Prometaphase The role of GTSE1 in G2/M progression after G2 checkpoint Carboxyterminal post-translational modifications of tubulin Carboxyterminal post-translational modifications of tubulin HCMV Early Events Assembly and cell surface presentation of NMDA receptors Activation of AMPK downstream of NMDARs Aggrephagy Aggrephagy EML4 and NUDC in mitotic spindle formation Sealing of the nuclear envelope (NE) by ESCRT-III Kinesins
Drugs		CYT997 Phenethyl Isothiocyanate	Raloxifene
Diseases
GWAS		Mean corpuscular hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Red cell distribution width ( 32888494 27863252)	Plateletcrit ( 32888494) Vitiligo ( 27723757)
Interacting Genes		27 interacting genes: ACD ARL15 ARNT CHGB DISC1 DUX4 HDAC6 HGS HMMR LAMA4 LINC01554 PAFAH1B3 POT1 PSMD11 PTPRS RABAC1 RIC8A RPA2 RPLP1 SAT1 SDC3 SERPINB9 TERF1 TK1 TNIK TPT1 UPF2	28 interacting genes: BRD7 CASP1 CASP4 CCDC90B COPS6 CRMP1 ECH1 EEF1A1 ERG28 GAPDH GBP2 GDF9 GZMB IGSF21 LRIF1 MED31 PLEKHM1 PRPF40A RBM48 SETDB1 TLE1 TP53 TRAF5 TUBB2A UBR1 UNC119 XRCC6 ZHX1
Entrez ID		7280	5272
HPRD ID			03480
Ensembl ID		ENSG00000137267	ENSG00000170542
Uniprot IDs		Q13885	A0A024QZT4 P50453
PDB IDs
Enriched GO Terms of Interacting Partners?
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