TGFB1I1 and MAPK15

Data Source:
HPRD (in vivo)

		TGFB1I1	MAPK15
Description		transforming growth factor beta 1 induced transcript 1	mitogen-activated protein kinase 15
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Cytoskeleton Plasma Membrane Focal Adhesion Nuclear Matrix Collagen-containing Extracellular Matrix	Extracellular Region Nucleus Cytoplasm Autophagosome Golgi Apparatus Centriole Cell-cell Junction Bicellular Tight Junction Axoneme Cytoplasmic Vesicle Ciliary Basal Body Meiotic Spindle
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Metal Ion Binding Roundabout Binding Androgen Receptor Binding I-SMAD Binding	Chromatin Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity MAP Kinase Activity Protein Binding ATP Binding Kinase Activity SH3 Domain Binding
	Biological Process	Cell Adhesion Negative Regulation Of Cell Population Proliferation Response To Heat Positive Regulation Of Epithelial To Mesenchymal Transition Wnt Signaling Pathway Morphogenesis Of Embryonic Epithelium Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Ubiquitin-dependent SMAD Protein Catabolic Process Epithelial Cell Differentiation Cell Fate Commitment Negative Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated	MAPK Cascade Regulation Of COPII Vesicle Coating Cellular Response To DNA Damage Stimulus Endoplasmic Reticulum Organization Positive Regulation Of Cell Population Proliferation Regulation Of Autophagy Negative Regulation Of Cell Migration Positive Regulation Of Telomere Maintenance Via Telomerase Intracellular Signal Transduction Protein Autophosphorylation Positive Regulation Of Telomerase Activity Dopamine Uptake Regulation Of Cilium Assembly Positive Regulation Of Telomere Capping Protein Localization To Ciliary Transition Zone Positive Regulation Of Metaphase/anaphase Transition Of Meiosis I Positive Regulation Of Spindle Assembly
Pathways
Drugs			Acetylsalicylic acid Minocycline Fostamatinib
Diseases
GWAS		Metabolite levels ( 23823483)	Obesity-related traits ( 23251661)
Interacting Genes		29 interacting genes: AR CBLB CBLC CDKN2B CRKL CSK EP300 FKBP1A GIT1 GIT2 GP1BB HIPK3 HSPB1 ITGA4 MAPK15 NEDD4L NR3C1 PLA2G3 PTK2 PTK2B PTPN12 SDC4 SLC6A3 SMAD7 SVIL TGFBR2 TRAF4 UBQLN4 VCL	8 interacting genes: CLIC3 CSK GABARAP GABARAPL1 MBP NR3C1 SRC TGFB1I1
Entrez ID		7041	225689
HPRD ID		03831	16867
Ensembl ID		ENSG00000140682	ENSG00000181085
Uniprot IDs		A0A024QZE7 O43294	Q8TD08
PDB IDs
Enriched GO Terms of Interacting Partners?
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