ACTC1 and KPTN

Data Source:
HPRD (in vivo)

		ACTC1	KPTN
Description		actin alpha cardiac muscle 1	kaptin, actin binding protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Dynactin Complex Actin Filament Focal Adhesion Membrane Sarcomere Lamellipodium Filopodium I Band Cell Body Extracellular Exosome Blood Microparticle	Lysosomal Membrane Lamellipodium Filamentous Actin Stereocilium Postsynaptic Actin Cytoskeleton KICSTOR Complex
	Molecular Function	ATP Binding ATPase Activity Myosin Binding	Actin Filament Binding
	Biological Process	Actin Filament Organization Positive Regulation Of Gene Expression Actin Filament-based Movement Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Actomyosin Structure Organization Actin-myosin Filament Sliding Response To Drug Response To Ethanol Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Heart Contraction Cardiac Muscle Contraction Mesenchyme Migration	Actin Filament Organization Cellular Response To Amino Acid Starvation Cellular Response To Glucose Starvation Protein Localization To Lysosome Negative Regulation Of TORC1 Signaling
Pathways		Striated Muscle Contraction	Amino acids regulate mTORC1
Drugs
Diseases		Hypertrophic cardiomyopathy (HCM) Atrial septal defect Dilated cardiomyopathy (DCM)
GWAS		Axial length ( 24144296) Refractive error ( 32231278 20835239)
Interacting Genes		41 interacting genes: ABLIM3 ABRA ACTB ACTN4 ACTR2 AFAP1 ANG ASH2L BCL11A C1QTNF9 CAPN1 CFL1 DMD DMTN DYNLL1 EZR FBXO7 FSCN1 GAPDH GC HSPB1 HSPB2 KAT14 KLHL17 KLHL2 KPTN LASP1 MIB2 MPC1 MYLK PLEC PRKCE SCIN SLC4A1 SYNE1 SYNE2 TNNI3K TWF1 UBC WAS WIPF1	3 interacting genes: ACTC1 APP SRPK1
Entrez ID		70	11133
HPRD ID		00015	17241
Ensembl ID		ENSG00000159251	ENSG00000118162
Uniprot IDs		B3KPP5 P68032	A0A384NLB4 Q9Y664
PDB IDs
Enriched GO Terms of Interacting Partners?
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