Wiki-Pi
About
Search
Browse
People
Updates
Search
TDGF1 and ACVR1B
Data Source:
BioGRID
(pull down, pull down)
HPRD
(in vivo)
TDGF1
ACVR1B
Description
teratocarcinoma-derived growth factor 1
activin A receptor type 1B
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Plasma Membrane
Cell Surface
Apical Plasma Membrane
Extrinsic Component Of Plasma Membrane
Anchored Component Of Membrane
Membrane Raft
Cytosol
Plasma Membrane
Integral Component Of Plasma Membrane
Cell Surface
Receptor Complex
Activin Receptor Complex
Molecular Function
Signaling Receptor Binding
Protein Binding
Growth Factor Activity
Nodal Binding
Activin Receptor Binding
Protein Serine/threonine Kinase Activity
Transmembrane Receptor Protein Serine/threonine Kinase Activity
Protein Binding
ATP Binding
Activin Receptor Activity, Type I
Activin-activated Receptor Activity
Growth Factor Binding
Ubiquitin Protein Ligase Binding
Inhibin Binding
SMAD Binding
Metal Ion Binding
Activin Binding
Biological Process
Activation Of MAPK Activity
Blood Vessel Development
Morphogenesis Of A Branching Structure
Cell Migration Involved In Sprouting Angiogenesis
Epidermal Growth Factor Receptor Signaling Pathway
Determination Of Left/right Symmetry
Heart Development
Positive Regulation Of Cell Population Proliferation
Anterior/posterior Axis Specification, Embryo
Embryo Development Ending In Birth Or Egg Hatching
Anterior/posterior Pattern Specification
Regulation Of Signal Transduction
Positive Regulation Of Endothelial Cell Migration
Peptidyl-serine Phosphorylation
Cell Differentiation
Positive Regulation Of Cell Migration
Mammary Gland Development
Somatic Stem Cell Population Maintenance
Cellular Response To Hepatocyte Growth Factor Stimulus
Nodal Signaling Pathway
Negative Regulation Of Apoptotic Process
Cellular Response To Fibroblast Growth Factor Stimulus
Anatomical Structure Development
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Cellular Response To Interferon-gamma
Cellular Response To Interleukin-6
Cellular Response To Tumor Necrosis Factor
Cellular Response To Epidermal Growth Factor Stimulus
G1/S Transition Of Mitotic Cell Cycle
In Utero Embryonic Development
Hair Follicle Development
Regulation Of Transcription, DNA-templated
Protein Phosphorylation
Signal Transduction
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Nervous System Development
Central Nervous System Development
Negative Regulation Of Gene Expression
Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation
Peptidyl-threonine Phosphorylation
Negative Regulation Of Cell Growth
Activin Receptor Signaling Pathway
Positive Regulation Of Activin Receptor Signaling Pathway
Nodal Signaling Pathway
Positive Regulation Of Erythrocyte Differentiation
Positive Regulation Of Transcription By RNA Polymerase II
Development Of Primary Female Sexual Characteristics
Protein Autophosphorylation
Cellular Response To Growth Factor Stimulus
Extrinsic Apoptotic Signaling Pathway
Positive Regulation Of Trophoblast Cell Migration
Pathways
Signaling by NODAL
Regulation of signaling by NODAL
POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation
Signaling by NODAL
Regulation of signaling by NODAL
Signaling by Activin
Drugs
ATP
Fostamatinib
Diseases
GWAS
Blood protein levels (
29875488
28240269
)
Metabolite levels (
23823483
)
Refractive error (
32231278
)
Adenocarcinoma (
26732429
)
Age-related hearing impairment (
24939585
)
Granulocyte count (
27863252
)
Hematocrit (
29403010
)
Hemoglobin (
29403010
)
Lung cancer (
26732429
)
Neutrophil count (
27863252
)
Post bronchodilator FEV1/FVC ratio (
26634245
)
Sum basophil neutrophil counts (
27863252
)
Sum neutrophil eosinophil counts (
27863252
)
Urate levels (
23263486
)
Interacting Genes
22 interacting genes:
ACVR1
ACVR1B
ACVR1C
ACVR2A
ACVR2B
ANG
AP2S1
BAG6
BMP4
BMP6
BMP7
BMPR1A
BMPR2
COPS6
FARSA
FBLN1
GDF3
GDF9
INHBB
LRIF1
NODAL
TGFBR2
22 interacting genes:
ACVR2B
BAG6
BAMBI
BMPR2
FKBP1A
IGSF1
INHBA
INHBB
INHBC
NEDD4L
NODAL
OS9
OTUB1
PRKACB
RXRA
SMAD2
SMAD4
SMAD7
SNX1
SNX2
TDGF1
TGFBRAP1
Entrez ID
6997
91
HPRD ID
01757
03193
Ensembl ID
ENSG00000241186
ENSG00000135503
Uniprot IDs
F5H1T8
P13385
P36896
PDB IDs
Enriched GO Terms of Interacting Partners
?
Tagcloud
?
Tagcloud (Difference)
?
Tagcloud (Intersection)
?