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SUPT5H and ZNF496
Data Source:
BioGRID
(two hybrid)
SUPT5H
ZNF496
Description
SPT5 homolog, DSIF elongation factor subunit
zinc finger protein 496
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
DSIF Complex
Nucleus
Molecular Function
Chromatin Binding
RNA Binding
MRNA Binding
Protein Binding
Enzyme Binding
Protein Heterodimerization Activity
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA Binding
Protein Binding
Metal Ion Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Transcription By RNA Polymerase II
Transcription Elongation From RNA Polymerase II Promoter
7-methylguanosine MRNA Capping
Positive Regulation Of Macroautophagy
Negative Regulation Of DNA-templated Transcription, Elongation
Positive Regulation Of DNA-templated Transcription, Elongation
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Viral Transcription
Negative Regulation Of MRNA Polyadenylation
Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Transcription, DNA-templated
Pathways
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of HIV elongation complex in the absence of HIV Tat
Formation of the HIV-1 Early Elongation Complex
RNA Pol II CTD phosphorylation and interaction with CE during HIV infection
Formation of HIV-1 elongation complex containing HIV-1 Tat
Formation of HIV-1 elongation complex containing HIV-1 Tat
Pausing and recovery of Tat-mediated HIV elongation
Abortive elongation of HIV-1 transcript in the absence of Tat
Tat-mediated HIV elongation arrest and recovery
Tat-mediated elongation of the HIV-1 transcript
HIV elongation arrest and recovery
Pausing and recovery of HIV elongation
RNA Polymerase II Pre-transcription Events
TP53 Regulates Transcription of DNA Repair Genes
RNA polymerase II transcribes snRNA genes
mRNA Capping
RNA Polymerase II Transcription Elongation
RNA Pol II CTD phosphorylation and interaction with CE
Generic Transcription Pathway
Drugs
Diseases
GWAS
Neutrophil count (
32888494
)
White blood cell count (
32888494
)
Chromium levels (
26025379
)
Platelet distribution width (
32888494
)
Interacting Genes
45 interacting genes:
C9orf78
CCNH
CCNT1
CCNT2
CDK7
CDK9
CEP55
CSNK2A1
DBN1
DCAF6
FHL3
GOLGA2
GTF3C1
H2AX
HSPB1
HTATSF1
IK
IKBKG
LMAN2
MAD1L1
MAML3
MNAT1
PCBD1
PHYHIP
PIN1
PNO1
POLR2A
PPIA
PPP2R2D
PRMT1
PRMT5
SAP30BP
SIK1
SNX4
SSBP3
SUMO2
SUPT4H1
TERF1
TEX11
TLE5
XRCC5
ZBTB3
ZFYVE9
ZNF496
ZNF512B
23 interacting genes:
ARR3
CBX3
JADE2
NR3C1
NSD1
PGBD1
POLR3D
PPARG
RAI1
RNF8
SCAND1
SSX3
SUMO2
SUMO3
SUPT5H
TRIM28
ZKSCAN4
ZNF446
ZNF483
ZSCAN12
ZSCAN21
ZSCAN22
ZZZ3
Entrez ID
6829
84838
HPRD ID
03655
15805
Ensembl ID
ENSG00000196235
ENSG00000162714
Uniprot IDs
O00267
Q96IT1
PDB IDs
2DO3
2E6Z
2E70
3H7H
4L1U
5OHO
5OHQ
5OIK
5U98
6EQY
6ER0
6GMH
6GML
6TED
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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