SMN2 and FNDC11

Data Source:
BioGRID (two hybrid)

		SMN2	FNDC11
Description		survival of motor neuron 2, centromeric	fibronectin type III domain containing 11
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Cajal Body Nuclear Body Z Disc Axon SMN Complex SMN-Sm Protein Complex Cytoplasmic Ribonucleoprotein Granule Neuron Projection Perikaryon Gemini Of Coiled Bodies
	Molecular Function	RNA Binding Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Spliceosomal Complex Assembly Spliceosomal SnRNP Assembly DNA-templated Transcription, Termination Nervous System Development Import Into Nucleus
Pathways		snRNP Assembly
Drugs		Nusinersen
Diseases		Spinal muscular atrophy (SMA), including: SMA type I (SMA1) / Werdning-Hoffman disease; SMA type II (SMA2); SMA type III (SMA3) / Kugeleberg-Welander disease; SMA type IV (SMA4); X-linked SMA 2 (SMAX2); X-linked distal SMA 3 (DSMAX); Distal SMA autosomal recessive type 4 (DSMA4); Congenital distal spinal muscular atrophy (SMAL); SMA proximal adult autosomal dominant (SMAPAD)
GWAS
Interacting Genes		36 interacting genes: BLOC1S6 BYSL CHTOP DDX20 DHX9 EHHADH FAM9B FBL FNDC11 GAR1 GEMIN2 HNRNPUL1 IQUB KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP6-1 KRTAP6-2 MAGED1 POLR1C POLR2A PPIG SMN1 SNRPB SNRPB2 SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SNU13 SPANXN2 TIAL1 USP9X VPS28	44 interacting genes: AP1B1 ARL5B CALCOCO2 CCDC102B CCDC85B CDA CDCA4 CDKN1A CERCAM CINP COG6 FAM9B GOLGA2 GPBP1 HGS HMBOX1 ID2 KRT34 KRT40 KRTAP19-6 LZTS2 MAGEA12 MDFI MGAT5B MIS18A MTUS2 PDLIM7 PSMA1 RBPMS REL RNF125 SCNM1 SERTAD1 SMN1 SMN2 SORBS3 SSX2IP TRAF2 TRIM27 UBQLN2 ZBED1 ZNF48 ZNRD2 ZRANB1
Entrez ID		6607	79025
HPRD ID		09036	14682
Ensembl ID		ENSG00000205571	ENSG00000125531
Uniprot IDs		B4DP61 E7EQZ4 Q16637	Q9BVV2
PDB IDs		1G5V 1MHN 2LEH 4A4E 4A4G 4GLI 4QQ6 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU
Enriched GO Terms of Interacting Partners?
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