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NMNAT1 and FLOT2
Data Source:
BioGRID
(two hybrid)
NMNAT1
FLOT2
Description
nicotinamide nucleotide adenylyltransferase 1
flotillin 2
Image
No pdb structure
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Nuclear Body
Uropod
Endosome
Plasma Membrane
Caveola
Adherens Junction
Focal Adhesion
Membrane
Basolateral Plasma Membrane
Apical Plasma Membrane
Flotillin Complex
Lamellipodium
Endocytic Vesicle
Cortical Actin Cytoskeleton
Cytoplasmic Vesicle
Vesicle
Intracellular Membrane-bounded Organelle
Cell-cell Contact Zone
Perinuclear Region Of Cytoplasm
Extracellular Exosome
Molecular Function
Nicotinamide-nucleotide Adenylyltransferase Activity
Nicotinate-nucleotide Adenylyltransferase Activity
Protein Binding
ATP Binding
Identical Protein Binding
Protein Binding
Biological Process
Nucleotide Biosynthetic Process
NAD Biosynthetic Process
Response To Wounding
NAD Metabolic Process
Positive Regulation Of MAPK Cascade
Negative Regulation Of Neuron Apoptotic Process
Negative Regulation Of Apoptotic DNA Fragmentation
ATP Generation From Poly-ADP-D-ribose
Membrane Raft Assembly
Cell Adhesion
Epidermis Development
Negative Regulation Of Gene Expression
Regulation Of Heterotypic Cell-cell Adhesion
Regulation Of Toll-like Receptor 3 Signaling Pathway
Protein Localization To Plasma Membrane Raft
Regulation Of Myoblast Differentiation
Protein Stabilization
Positive Regulation Of NF-kappaB Transcription Factor Activity
Protein Localization To Plasma Membrane
Negative Regulation Of Amyloid Precursor Protein Catabolic Process
Positive Regulation Of Establishment Of T Cell Polarity
Pathways
Nicotinate metabolism
RIPK1-mediated regulated necrosis
Regulation of necroptotic cell death
Synaptic adhesion-like molecules
Drugs
Nicotinamide Mononucleotide
Deamido-Nad+
Diseases
GWAS
Resting heart rate (
27798624
)
Mean corpuscular hemoglobin (
29403010
)
Red blood cell count (
27863252
)
Interacting Genes
19 interacting genes:
APP
BANP
CCNC
FLOT2
GORASP2
KPNA1
KPNA2
KPNA3
KPNA5
KPNA6
MSX1
NEK3
NFATC2IP
NTRK2
PICK1
RNF4
SIK1
SIRT1
TDO2
11 interacting genes:
APP
CAV1
CAV2
DXO
FLOT1
FYN
HGS
MAGEB4
NMNAT1
SPATA24
UBC
Entrez ID
64802
2319
HPRD ID
16369
00580
Ensembl ID
ENSG00000173614
ENSG00000132589
Uniprot IDs
A0A024R4E1
B1AN62
Q9HAN9
A0A024QZ62
J3QLD9
Q14254
Q6FG43
Q9BTI6
PDB IDs
1GZU
1KKU
1KQN
1KQO
1KR2
Enriched GO Terms of Interacting Partners
?
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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