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RPLP1 and PDCD4
Data Source:
HPRD
(in vitro)
RPLP1
PDCD4
Description
ribosomal protein lateral stalk subunit P1
programmed cell death 4
Image
GO Annotations
Cellular Component
Cytosol
Focal Adhesion
Cytosolic Large Ribosomal Subunit
Nucleus
Cytoplasm
Cytosol
Molecular Function
Structural Constituent Of Ribosome
Protein Binding
Protein Kinase Activator Activity
Ribonucleoprotein Complex Binding
RNA Binding
Protein Binding
Biological Process
Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay
Cytoplasmic Translation
Translation
Translational Initiation
Translational Elongation
SRP-dependent Cotranslational Protein Targeting To Membrane
Viral Transcription
Activation Of Protein Kinase Activity
Apoptotic Process
Cell Aging
BMP Signaling Pathway
Interleukin-12-mediated Signaling Pathway
Negative Regulation Of Apoptotic Process
Negative Regulation Of JUN Kinase Activity
Negative Regulation Of Cell Cycle
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Inflammatory Response
Epithelial To Mesenchymal Transition Involved In Cardiac Fibroblast Development
Cellular Response To Lipopolysaccharide
Negative Regulation Of Cytokine Production Involved In Inflammatory Response
Positive Regulation Of NIK/NF-kappaB Signaling
Negative Regulation Of Vascular Associated Smooth Muscle Cell Proliferation
Negative Regulation Of Myofibroblast Differentiation
Negative Regulation Of Vascular Associated Smooth Muscle Cell Differentiation
Positive Regulation Of Vascular Associated Smooth Muscle Cell Apoptotic Process
Positive Regulation Of Endothelial Cell Apoptotic Process
Pathways
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Response of EIF2AK4 (GCN2) to amino acid deficiency
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs
Diseases
GWAS
Chronic lymphocytic leukemia (
28165464
24292274
23770605
)
Male-pattern baldness (
27182965
)
Non-response to citalopram or escitalopram and depression (
27622933
)
Fish- and plant-related diet (
32066663
)
Interacting Genes
35 interacting genes:
ANKRD13B
ASCC2
ATP5MF
BRD7
C11orf58
C15orf39
CDIPT
CDK2AP2
CLIC1
CSNK2A1
EEF1A1
GEMIN7
GSK3B
LRIF1
MAP1LC3B
MPC2
NSF
NUDT21
NUDT3
PDCD4
PFDN1
PPP2CB
PTN
RCHY1
RPA2
RPLP2
RPS6KA6
SAT1
SGO1
SUOX
TAB1
TPT1
TUBB2A
UBE2D3
XRCC6
16 interacting genes:
APOE
BTRC
CSNK2A1
EIF4A2
EIF4A3
EIF4G1
IBTK
LRRK1
PSEN1
PSEN2
RPL5
RPLP1
RPS13
RPS6KA1
SKP2
SUMO2
Entrez ID
6176
27250
HPRD ID
01611
10549
Ensembl ID
ENSG00000137818
ENSG00000150593
Uniprot IDs
A0A024R608
P05386
B4DKX4
Q53EL6
PDB IDs
2LBF
4BEH
4V6X
2GGF
2KZT
2RG8
2ZU6
3EIJ
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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