RALA and EXOC6B

Data Source:
HPRD (in vitro)

		RALA	EXOC6B
Description		RAS like proto-oncogene A	exocyst complex component 6B
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Focal Adhesion Cell Surface Endocytic Vesicle Cytoplasmic Vesicle Membrane Cleavage Furrow Extracellular Exosome Flemming Body	Exocyst Membrane
	Molecular Function	GTPase Activity Protein Binding GTP Binding Myosin Binding GDP Binding Ubiquitin Protein Ligase Binding Edg-2 Lysophosphatidic Acid Receptor Binding ATPase Binding	Protein Binding
	Biological Process	Neural Tube Closure Exocytosis Chemotaxis Cell Cycle Signal Transduction Ras Protein Signal Transduction Regulation Of Exocytosis Actin Cytoskeleton Reorganization Interleukin-12-mediated Signaling Pathway Cell Division Positive Regulation Of Filopodium Assembly Membrane Raft Localization Membrane Organization	Exocytosis Golgi To Plasma Membrane Transport Vesicle Docking Involved In Exocytosis Protein Transport
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane p38MAPK events Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs		Guanosine-5'-Diphosphate
Diseases
GWAS			Diastolic blood pressure ( 30224653 27841878) Height ( 31562340) Malaria ( 31844061) Systolic blood pressure ( 27841878)
Interacting Genes		30 interacting genes: ARF1 CALM1 CNKSR2 CTCF EXOC1 EXOC2 EXOC3 EXOC4 EXOC5 EXOC6B EXOC7 EXOC8 FLNA GLS2 HSPB1 LSM2 PIH1D2 PLCD1 PLD1 PPP2R1B RAB34 RAB8B RALBP1 RALGPS1 RASSF5 REPS1 RGL2 RGL4 SMAD4 YBX3	4 interacting genes: EXOC5 MTERF1 RALA SHTN1
Entrez ID		5898	23233
HPRD ID		01549	19418
Ensembl ID		ENSG00000006451	ENSG00000144036
Uniprot IDs		P11233	A0A0U1RRB6 Q9Y2D4
PDB IDs		1UAD 1ZC3 1ZC4 2A78 2A9K 2BOV 6P0I 6P0J 6P0K 6P0L 6P0M 6P0N 6P0O
Enriched GO Terms of Interacting Partners?
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